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Plasma Nortriptyline and Clinical Response
Australian & New Zealand Journal of Psychiatry, 1975(1975). Plasma Nortriptyline and Clinical Response. Australian and New Zealand Journal of Psychiatry: Vol. 9, No. 4, pp. 249-253.
B, Davies, G, Burrows, B, Scoggins
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Plasma nortriptyline and clinical response
Clinical Pharmacology & Therapeutics, 1974The relationship of plasma nortriptyline levels to the clinical response of 80 depressed patients was studied. Plasma nortriptyline levels were estimated 4 weeks after commencing treatment. Percentage change in the Hamilton Depression Rating Scale was used to measure clinical response. There was no simple relationship between these two measures. Twelve
G, Burrows +3 more
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Cimetidine plasma concentration-response relationships
Clinical Pharmacology and Therapeutics, 1981Cimetidine plasma concentration-response relationships were investigated in six healthy subjects using suppression of gastric acid secretion under continuous pentagastrin stimulation (1.5 micrograms/kg/hr) as a test model. With the Hill equation the sigmoid was preferable to the linear relationship between plasma concentration and effect, and there ...
R, Gugler +3 more
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Plasma Fibronectin Response to Sepsis
The Journal of Trauma: Injury, Infection, and Critical Care, 1983Plasma fibronectin (PFN) is a high molecular weight adhesive glycoprotein. Following trauma or sepsis PFN is acutely depleted, with rapid restoration of normal or supranormal levels after 24 to 48 hours. Cecal ligation with perforation provides an animal model of surgical trauma combined with polymicrobial sepsis.
T S, Velky, J C, Yang, A G, Greenburg
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Low-frequency responses in dusty plasmas
Journal of Plasma Physics, 2005In the parameter regime where the ion/electron-dust collisions dominate with respect to the plasma binary collisions, the presence of plasma fluxes to the dust surfaces and dust charge fluctuations can significantly modify the dusty plasma response to low-frequency perturbations, with respect to the multi-component response (no charging collisions ...
MARMOLINO, Ciro, DE ANGELIS U.
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Desipramine Plasma Concentration and Antidepressant Response
Archives of General Psychiatry, 1982The relationship of desipramine hydrochloride plasma concentration and antidepressant response was determined in 30 depressed inpatients treated for three weeks with desipramine. All patients had a nondelusional unipolar depression, met DSM-III criteria for major depressive episode with melancholia, and had a Hamilton score of 18 or greater after one ...
J C, Nelson +3 more
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Nortriptyline plasma levels and therapeutic response
Clinical Pharmacology & Therapeutics, 1976Eighteen depressed outpatients were treatedfor 6 wk with a mean daily dose of 121 mg of nortriptyline. The mean plasma level was 138 ng/ml during treatment. Therapeutic response was monitored by the Zung SelfâRating Depression Scale and the Hamilton Depression Scale administrered by two psychiatrists blind to the tricyclic used, dose, and plasma levels.
V E, Ziegler +4 more
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Escitalopram plasma levels and antidepressant response
European Neuropsychopharmacology, 2017Major Depression Disorder (MDD) has a highly variable treatment response due to the large inter-individual variation in the pharmacokinetics and pharmacodynamics of drug treatments. In detail the correlation between plasma level and efficacy has been much debated. Among first-line drugs for MDD, one of the most used is escitalopram.
Florio, Vincenzo +4 more
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