Results 161 to 170 of about 7,662,476 (212)

Plasma nortriptyline and clinical response

Clinical Pharmacology & Therapeutics, 1974
The relationship of plasma nortriptyline levels to the clinical response of 80 depressed patients was studied. Plasma nortriptyline levels were estimated 4 weeks after commencing treatment. Percentage change in the Hamilton Depression Rating Scale was used to measure clinical response. There was no simple relationship between these two measures. Twelve
G, Burrows, B A, Scoggins, L R, Turecek, B, Davies   +3 more
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Plasma Fibronectin Response to Sepsis

The Journal of Trauma: Injury, Infection, and Critical Care, 1983
Plasma fibronectin (PFN) is a high molecular weight adhesive glycoprotein. Following trauma or sepsis PFN is acutely depleted, with rapid restoration of normal or supranormal levels after 24 to 48 hours. Cecal ligation with perforation provides an animal model of surgical trauma combined with polymicrobial sepsis.
T S, Velky, J C, Yang, A G, Greenburg
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Desipramine Plasma Concentration and Antidepressant Response

Archives of General Psychiatry, 1982
The relationship of desipramine hydrochloride plasma concentration and antidepressant response was determined in 30 depressed inpatients treated for three weeks with desipramine. All patients had a nondelusional unipolar depression, met DSM-III criteria for major depressive episode with melancholia, and had a Hamilton score of 18 or greater after one ...
J C, Nelson, P, Jatlow, D M, Quinlan, M B, Bowers   +3 more
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Low-frequency responses in dusty plasmas

Journal of Plasma Physics, 2005
In the parameter regime where the ion/electron-dust collisions dominate with respect to the plasma binary collisions, the presence of plasma fluxes to the dust surfaces and dust charge fluctuations can significantly modify the dusty plasma response to low-frequency perturbations, with respect to the multi-component response (no charging collisions ...
MARMOLINO, Ciro, DE ANGELIS U.
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Escitalopram plasma levels and antidepressant response

European Neuropsychopharmacology, 2017
Major Depression Disorder (MDD) has a highly variable treatment response due to the large inter-individual variation in the pharmacokinetics and pharmacodynamics of drug treatments. In detail the correlation between plasma level and efficacy has been much debated. Among first-line drugs for MDD, one of the most used is escitalopram.
Florio, Vincenzo, Porcelli, Stefano, Saria, Alois, Serretti, Alessandro, Conca, Andreas   +4 more
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Duloxetine plasma level and antidepressant response

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2019
Major Depressive Disorder (MDD) is associated with a high rate of inadequate treatment response, which is mainly due to the large inter-individual genetic variability in pharmacokinetic and pharmacodynamic targets of antidepressant drugs. Little is still known about the exact association between plasma level of first-line antidepressants and clinical ...
De Donatis, Domenico, Florio, Vincenzo, Porcelli, Stefano, Saria, Alois, Mercolini, Laura, Serretti, Alessandro, Conca, Andreas   +6 more
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Clozapine response and plasma catecholamines and their metabolites

Psychiatry Research, 1993
The atypical neuroleptic clozapine has an unusual profile of clinical effects and a distinctive spectrum of pharmacological actions. Plasma measures of catecholamines and their metabolites have been used in the past to study the action of typical neuroleptics.
A I, Green, M Y, Alam, J T, Sobieraj, K M, Pappalardo, C, Waternaux, C, Salzman, A F, Schatzberg, J J, Schildkraut   +7 more
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Plasma biopterin levels and tetrahydrobiopterin responsiveness

Molecular Genetics and Metabolism, 2005
Tetrahydrobiopterin (BH4) responsive hyperphenylalaninemia (HPA) with a mutant phenylalanine hydroxylase (PAH) gene was found during neonatal screening for PKU. This study determined blood BH4 and phenylalanine in two patients with hyperphenylalaninemia following oral load with BH4 10 mg/kg. Our patients underwent neonatal screening for PKU, had normal
Haruo, Shintaku, Hiroki, Fujioka, Yoshitomo, Sawada, Minoru, Asada, Tsunekazu, Yamano   +4 more
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Amitriptyline plasma levels and therapeutic response

Clinical Pharmacology & Therapeutics, 1976
Eighteen depressed outpatients were treatedfor 6 wk with amitriptyline. Clinical improvement was monitored using the Hamilton Depression Rating Scale administered by two psychiatrists blind to the tricyclic used for treatment, dosage, and plasma levels.
V E, Ziegler, B T, Co, J R, Taylor, P J, Clayton, J T, Biggs   +4 more
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Nortriptyline plasma levels and therapeutic response

Clinical Pharmacology & Therapeutics, 1976
Eighteen depressed outpatients were treatedfor 6 wk with a mean daily dose of 121 mg of nortriptyline. The mean plasma level was 138 ng/ml during treatment. Therapeutic response was monitored by the Zung Self‐Rating Depression Scale and the Hamilton Depression Scale administrered by two psychiatrists blind to the tricyclic used, dose, and plasma levels.
V E, Ziegler, P J, Clayton, J R, Taylor, B, Tee, J T, Biggs   +4 more
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