Results 301 to 310 of about 1,095,946 (360)
Role of AcrAB-TolC multidrug efflux pump in drug-resistance acquisition by plasmid transfer
Science, 2019 A race against time Clinically relevant antimicrobial resistance is largely spread via plasmids that disperse among bacteria during conjugation. How quickly can a resistance gene be expressed after transfer?
Sophie Nolivos +2 more
exaly +2 more sources
Persistence and reversal of plasmid-mediated antibiotic resistance
Nature Communications, 2017 In the absence of antibiotic-mediated selection, sensitive bacteria are expected to displace their resistant counterparts if resistance genes are costly. However, many resistance genes persist for long periods in the absence of antibiotics.
Allison J Lopatkin +2 more
exaly +2 more sources
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Current Biology, 2020
Plasmids are genetic elements that colonize and replicate in prokaryotic cells (Box 1). They are considered a major driving force of prokaryote evolution, as they can migrate between populations, making them potent agents of lateral DNA transfer and microbial warfare.
Tanita, Wein, Tal, Dagan
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Plasmids are genetic elements that colonize and replicate in prokaryotic cells (Box 1). They are considered a major driving force of prokaryote evolution, as they can migrate between populations, making them potent agents of lateral DNA transfer and microbial warfare.
Tanita, Wein, Tal, Dagan
openaire +2 more sources
2003
Bacterial plasmids are extra-chromosomal, covalently-closed circular (CCC) molecules of DNA that are capable of autonomous replication (1). Plasmids may contain genes for a variety of phenotypic traits, such as antibiotic resistance, virulence, or metabolic activities, although some plasmids comprise genes conferring no detectable phenotype and are ...
A P, Johnson, N, Woodford
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Bacterial plasmids are extra-chromosomal, covalently-closed circular (CCC) molecules of DNA that are capable of autonomous replication (1). Plasmids may contain genes for a variety of phenotypic traits, such as antibiotic resistance, virulence, or metabolic activities, although some plasmids comprise genes conferring no detectable phenotype and are ...
A P, Johnson, N, Woodford
openaire +2 more sources
2003
Genetic manipulation of mycobacteria has historically been difficult. This is in large part due to the impenetrable nature of the cell wall, resulting in difficulty both in introducing DNA into the bacterium and subsequent isolation of intact plasmid DNA.
N, Casali, S, Ehrt
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Genetic manipulation of mycobacteria has historically been difficult. This is in large part due to the impenetrable nature of the cell wall, resulting in difficulty both in introducing DNA into the bacterium and subsequent isolation of intact plasmid DNA.
N, Casali, S, Ehrt
openaire +2 more sources
Plasmid Segregation Mechanisms
Annual Review of Genetics, 2005Bacterial plasmids encode partitioning (par) loci that ensure ordered plasmid segregation prior to cell division. par loci come in two types: those that encode actin-like ATPases and those that encode deviant Walker-type ATPases. ParM, the actin-like ATPase of plasmid R1, forms dynamic filaments that segregate plasmids paired at mid-cell to daughter ...
Ebersbach G, Gerdes K
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Ti plasmids of Agrobacterium as conjugative plasmids
Nature, 1977THE relationship of the plant-oncogenic properties of Agrobacterium tumefaciens to the presence in these strains of large plasmids (the Ti plasmids) has now been convincingly demonstrated in several ways: oncogenic strains cured of the Ti plasmid lose their oncogenicity irreversibly1–3; transfer of Ti plasmids to non-oncogenic plasmidless strains ...
C, Genetello +5 more
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Plasmid Profile Typing and Plasmid Fingerprinting
2003Plasmids are extra-chromosomal molecules of deoxyribonucleic acid (DNA) capable of autonomous replication. Such molecules have been identified in many bacterial genera and usually exist as covalently closed circular (CCC) molecules. Plasmids range in size from less than one megaDalton (MDa) to several hundred MDa.
E J, Threlfall, N, Woodford
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1983
This chapter describes the degradative plasmids. Microorganisms play a major role in the degradation of the products and by-products of the activities of animals and plants and other microorganisms. The failure of microorganisms to rapidly recycle any of these compounds results in their accumulation in the environment and can lead to the phenomenon of ...
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This chapter describes the degradative plasmids. Microorganisms play a major role in the degradation of the products and by-products of the activities of animals and plants and other microorganisms. The failure of microorganisms to rapidly recycle any of these compounds results in their accumulation in the environment and can lead to the phenomenon of ...
openaire +3 more sources
Plasmid Copy Number and Plasmid Stability
2003Many expression systems in research and industry use plasmids as vectors for the production of recombinant proteins or non-proteinous recombinant substances. Plasmids have an essential impact on productivity. Related factors are plasmid copy number, structural plasmid stability and segregational plasmid stability.
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