Results 301 to 310 of about 1,502,313 (400)
Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng
Molood Behbahanipour +11 more
wiley +1 more source
<i>Klebsiella pneumoniae</i> with Two Carbapenemases: Where Molecular Research Stands Now. [PDF]
Yu Q, Li G, Xu Q, Zhu Y.
europepmc +1 more source
Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao +4 more
wiley +1 more source
Advances in molecular adjuvants for nucleic acid vaccines. [PDF]
Hojecki CE +4 more
europepmc +1 more source
Dissolvable microneedle (MN) device containing Bacillus paralicheniformis. The polymeric matrix encapsulates and protects the bacteria, preserving their viability while enabling in situ production and release of γ‐polyglutamic acid. The bacteria are delivered into the skin via 500 µm‐long microneedles, and remain detectable on the skin 24 h post ...
Caroline Hali Alperovitz +3 more
wiley +1 more source
Identification of Plasma-Generated Reactive Species in Water and Their DNA-Damaging Effects on Plasmid and Lymphocyte DNA. [PDF]
Kyzek S +6 more
europepmc +1 more source
Plug‐and‐Play Centrifuge‐Only Device for Rapid Sepsis Diagnosis
A fully automated, centrifuge‐only device can isolate and concentrate bacteria from blood for rapid sepsis diagnosis. The device enables >3×$>3\times$ bacterial enrichment and removes >$>$99.9% of blood cells. The device supports direct downstream analysis via subculturing, MALDI‐TOF, and microfluidic detection of bacteria.
Mohammad Osaid +5 more
wiley +1 more source
Scarless gene disruption enabled by a dual-plasmid knockout platform in a clinical infant-derived <i>Bifidobacterium breve</i> strain. [PDF]
Gao Z, Feng L.
europepmc +1 more source

