Results 341 to 350 of about 1,502,313 (400)

Nanopore long-read only genome assembly of clinical Enterobacterales isolates is complete and accurate

Nagy D, Pennetta V, Rodger G, Hopkins K, Jones CR, The NEKSUS Consortium, Hopkins S, Crook D, Walker AS, Robotham J, Hopkins KL, Ledda A, Williams D, Hope R, Brown CS, Stoesser N, Lipworth S.   +16 more
europepmc   +1 more source

Plasmid-encoded tet(X) genes that confer high-level tigecycline resistance in Escherichia coli

Nature Microbiology, 2019
Tigecycline is one of the last-resort antibiotics to treat complicated infections caused by both multidrug-resistant Gram-negative and Gram-positive bacteria1.
Jian Sun, Chong Chen, Youjun Feng
exaly   +2 more sources

PlasFlow: predicting plasmid sequences in metagenomic data using genome signatures

Nucleic Acids Research, 2018
Plasmids are mobile genetics elements that play an important role in the environmental adaptation of microorganisms. Although plasmids are usually analyzed in cultured microorganisms, there is a need for methods that allow for the analysis of pools of ...
Pawel S Krawczyk, Andrzej Dziembowski
exaly   +2 more sources

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The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA

Nature, 2010
Rodolphe Barrangou, Patrick Boyaval, christophe Fremaux   +2 more
exaly   +2 more sources

Role of AcrAB-TolC multidrug efflux pump in drug-resistance acquisition by plasmid transfer

Science, 2019
A race against time Clinically relevant antimicrobial resistance is largely spread via plasmids that disperse among bacteria during conjugation. How quickly can a resistance gene be expressed after transfer?
Sophie Nolivos, Adeline Page, Frédéric Delolme   +2 more
exaly   +2 more sources

Persistence and reversal of plasmid-mediated antibiotic resistance

Nature Communications, 2017
In the absence of antibiotic-mediated selection, sensitive bacteria are expected to displace their resistant counterparts if resistance genes are costly. However, many resistance genes persist for long periods in the absence of antibiotics.
Allison J Lopatkin, Hannah R Meredith, Jaydeep K Srimani   +2 more
exaly   +2 more sources

Plasmid evolution

Current Biology, 2020
Plasmids are genetic elements that colonize and replicate in prokaryotic cells (Box 1). They are considered a major driving force of prokaryote evolution, as they can migrate between populations, making them potent agents of lateral DNA transfer and microbial warfare.
Tanita, Wein, Tal, Dagan
openaire   +2 more sources

Ti plasmids of Agrobacterium as conjugative plasmids

Nature, 1977
THE relationship of the plant-oncogenic properties of Agrobacterium tumefaciens to the presence in these strains of large plasmids (the Ti plasmids) has now been convincingly demonstrated in several ways: oncogenic strains cured of the Ti plasmid lose their oncogenicity irreversibly1–3; transfer of Ti plasmids to non-oncogenic plasmidless strains ...
A. De Picker, N. Van Larebeke, C. Genetello, M. Holsters, M. Van Montagu, J. Schell   +5 more
openaire   +3 more sources

Plasmid Profile Typing and Plasmid Fingerprinting

2003
Plasmids are extra-chromosomal molecules of deoxyribonucleic acid (DNA) capable of autonomous replication. Such molecules have been identified in many bacterial genera and usually exist as covalently closed circular (CCC) molecules. Plasmids range in size from less than one megaDalton (MDa) to several hundred MDa.
E. John Threlfall, Neil Woodford
openaire   +3 more sources