High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires+4 more
wiley +1 more source
Physical properties and gel electrophoresis behavior of R12-derived plasmid DNAs [PDF]
Susan F. Mickel+2 more
openalex +1 more source
Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson+12 more
wiley +1 more source
Transfer of chromosomal genes mediated by plasmid r68.45 in Rhodopseudomonas sphaeroides [PDF]
W. R. Sistrom
openalex +1 more source
A Sustainable Biotechnology Approach for Mineral Separation
Silver‑binding peptides are first identified through phage‐display screening, and then engineered into multifunctional and responsive peptides or proteins. These tailored biomolecules can selectively capture and aggregate silver particles or ions from complex mixtures, enabling rapid and efficient silver separation and recovery.
Guangze Yang+7 more
wiley +1 more source
How many plasmids can bacteria carry? A synthetic biology perspective. [PDF]
Kiattisewee C.
europepmc +1 more source
Chloramphenicol Resistance in Streptococcus pneumoniae: Enzymatic Acetylation and Possible Plasmid Linkage [PDF]
Annie Dang-Van+4 more
openalex +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth+2 more
wiley +1 more source
Pan-genus analysis and typing of antimicrobial resistance plasmids in Acinetobacter. [PDF]
Tobin LA, Lam MMC, Hamidian M.
europepmc +1 more source
plasmidSPAdes: Assembling Plasmids from Whole Genome Sequencing Data
D. Antipov+5 more
semanticscholar +1 more source