Results 281 to 290 of about 1,104,645 (398)

Characterization of a mini-ColC1 plasmid

, 1976
Vickers Hershfield, H W Boyer, Louise T. Chow, Donald R. Helinski   +3 more
openalex   +1 more source

Shedding Light on the Cellular Uptake Mechanisms of Bioactive Glass Nanoparticles as Controlled Intracellular Delivery Platforms: A Review of the Recent Literature

Advanced Healthcare Materials, EarlyView.
This review summarizes the main uptake pathways of bioactive glass nanoparticles (BGNs) and their intracellular localization, highlighting that BGNs are mainly internalized and entrapped within endosomes/lysosomes. Strategies for controlled intracellular ion release, with implications for targeted modulation of cell behavior, are discussed. The need to
Andrada‐Ioana Damian‐Buda, Aldo R. Boccaccini   +1 more
wiley   +1 more source

Topo IV is required to allow replisomes to converge and complete replication on the chromosome. [PDF]

PLoS Genet
Mokhtari PD, Seyedjavadi T, Liyanaarachchi TA, Courcelle CT, Courcelle J.   +4 more
europepmc   +1 more source

Ultraviolet light protection, enhancement of ultraviolet light mutagenesis, and mutator effect of plasmid R46 in Salmonella typhimurium

, 1976
Kristien Mortelmans, B. A. D. Stocker
openalex   +1 more source

Magnetic Resonance Imaging‐Based Quantification of Endosomal Escape Using Iron Oxide Nanoparticle‐Loaded Lipid Nanoparticles

Advanced Healthcare Materials, EarlyView.
The therapeutic efficacy of lipid nanoparticle(LNP)‐based drugs depends on endosomal escape. However, few methods are available for quantifying the efficiency of endosomal escape in vivo. Herein, a novel method for quantifying the endosomal escape efficiency index using magnetic resonance imaging is introduced.
Somin Lee, Jeongbin Park, Han Na Jung, Shengjun Li, Zhijun Lin, Hyung‐Jun Im   +5 more
wiley   +1 more source

Exploring the eco-evolutionary role of plasmids and defense systems in '<i>Fervidacidithiobacillus caldus</i>' extreme acidophile. [PDF]

Front Microbiol
Pacheco-Acosta S, Castro-Toro G, Rojas-Villalobos C, Valenzuela C, Haristoy JJ, Zapata-Araya A, Moya-Beltrán A, Sepúlveda-Rebolledo P, Pérez-Rueda E, Ulloa R, Giaveno A, Issotta F, Díez B, Beard S, Quatrini R.   +14 more
europepmc   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Fish TOLLIP manipulates ATG5 for autophagic degradation of STING to attenuate antiviral interferon responses. [PDF]

PLoS Pathog
Tian MZ, Wang YY, Cui BJ, Xu X, Zhou CJ, Zhang C, Li ZC, Hong MQ, Xu N, Chen DD, Lu LF, Li S.   +11 more
europepmc   +1 more source

Construction of biologically functional bacterial plasmids in vitro.

Proceedings of the National Academy of Sciences of the United States of America, 1973
S. Cohen, A. C. Chang, H. Boyer, R. Helling   +3 more
semanticscholar   +1 more source

Molecular Simulations of Polymer‐based Drug Nanocarriers: From Physical and Structural Properties to Controlled Release

Advanced Healthcare Materials, EarlyView.
Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao, Xin Jiang, Jinyu Li, Julien Nicolas, Tâp Ha‐Duong   +4 more
wiley   +1 more source