Results 291 to 300 of about 1,093,625 (405)

Plasmid Art

, 2018
Trabajo presentado en Plasmid Biology 2018, celebrado en Seattle (Estados Unidos) del 05 al 09 de agosto de 2018.
openaire   +1 more source

Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas

Advanced Materials, EarlyView.
ENDO lipid nanoparticles containing cholecalciferol as a fifth component demonstrate mRNA delivery to the pancreas with 99% selectivity, including beta cells. This platform shows minimal toxicity and sustained protein expression for up to 3 days in a dose‐dependent manner, offering a novel approach to pancreas‐specific mRNA delivery and gene therapy ...
Ivan Isaac, Luv Patel, Nguyen Tran, Amarnath Singam, DongSoo Yun, Prasun Guha, Seungman Park, Chandrabali Bhattacharya   +7 more
wiley   +1 more source

Porcine reproductive and respiratory syndrome virus NSP5 exploited UBE2L6 to promote viral replication via antagonising host RLRs and ISGylation. [PDF]

Vet Res
Zhu Z, Chen L, Zhang M, Lin Q, Yan Y, Wang W, Wen W, Zhang Z, Li X.   +8 more
europepmc   +1 more source

Genetic Surfaceome E. coli Reprogramming Enables Selective Water Oxidation

Advanced Materials, EarlyView.
A novel enzymatic material based on bilirubin oxidase (BOD) surface‐expressed on E. coli for effective electrocatalysis is reported. With this material, highly efficient and selective water oxidation is achieved, a critical half reaction for synthetic photosynthesis. Abstract Programming catalytic behavior at the microbial genome level is a frontier in
Graziela C. Sedenho, Jéssica C. Pacheco, Melanie Gut, Filipe C. D. A. Lima, Sunanda Dey, Frank N. Crespilho, Ariel L. Furst   +6 more
wiley   +1 more source

Breaking barriers in the sensitive and accurate mass determination of large DNA plasmids by mass photometry. [PDF]

Mol Ther Nucleic Acids
Ebberink EHTM, Deslignière E, Ruisinger A, Nuebel M, Thomann M, Heck AJR.   +5 more
europepmc   +1 more source

Nanostructured Protein Surfaces Inspired by Spider Silk

Advanced Materials, EarlyView.
Harnessing recombinant spider silk technology, bioengineered spidroin variants enable the creation of functionalized nanostructured coatings with tunable affinity for specific targets, supporting a broad range of applications ‐ from antifouling surfaces and targeted drug delivery to advanced cell therapies and precision bio‐patterning via lithography ...
Martin Humenik, Thomas Scheibel
wiley   +1 more source

High-level, plasmid-borne resistance to gentamicin in Streptococcus faecalis subsp. zymogenes

, 1979
T Horodniceanu, Lydie Bougueleret, Névine El-Solh, G Bieth, F Delbos   +4 more
openalex   +1 more source

Production of SARS-CoV-2 virus-like particles as a vaccine candidate in stable cell lines through inducible E and M protein expression. [PDF]

BMC Biotechnol
Liu Y, Chen Z, Yang L, Gan C, Tang J, Zheng Z, Ye J, Valencia CA, Chow HY, Dong B.   +9 more
europepmc   +1 more source

Advances and Strategies in Enhancing mRNA Cancer Vaccines

Advanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang, Shengqi Chen, Haijun Hu, Yenhui Ong, Qianqian Ni   +4 more
wiley   +1 more source

Genomic characterization of a multidrug-resistant <i>Citrobacter portucalensis</i> isolate co-harboring <i>bla</i> _<i>KPC-</i>2 and <i>bla</i> _<i>NDM-</i>1 on distinct plasmids. [PDF]

Front Microbiol
Huang J, Shen K, Chen K, Wu J, Zhu Y, Shi J.   +5 more
europepmc   +1 more source