Results 311 to 320 of about 3,479,441 (357)

Lipoprotein(a) inhibition of plasminogen activation by tissue-type plasminogen activator

Thrombosis Research, 1990
Here experimental evidence is presented demonstrating that Lp(a) inhibits the activation of Pg by the physiologic activator tissue-type plasminogen activator (t-PA) bound to fibrinogen fragments. The competitive inhibition constant, Kie, of the Lp(a) inhibition is 22 nM, or 8.6 mg/dL which corresponds to normal plasma ...
J M, Edelberg, M, Gonzalez-Gronow, S V, Pizzo   +2 more
openaire   +2 more sources

Kinetic studies of plasminogen activation by epithelial tissue plasminogen activator

Blood Coagulation & Fibrinolysis, 1990
Initial-rate kinetic studies of the activation of plasminogen by epithelial activator were performed in the absence and in the presence of fibrinogen and CNBr-digested fibrinogen, under assay conditions similar to those described by Hoylaerts et al. (J Biol Chem, 257, 2912, 1982).
A, Electricwala, R J, Ling, T, Atkinson
openaire   +2 more sources

Importance of the interaction between plasminogen and fibrin for plasminogen activation by tissue-type plasminogen activator

Thrombosis Research, 1984
The potentiating effect of fibrin monomer on plasminogen activation by tissue-type plasminogen activator is much more important with lys-plasminogen than with mini-plasminogen (which lacks the high affinity lysine-binding site important for binding to fibrin).
F W, Dunn, K, Deguchi, J, Soria, C, Soria, H R, Lijnen, G, Tobelem, J, Caen   +6 more
openaire   +2 more sources

Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS)

Journal of the American Medical Association (JAMA), 1995
W. Hacke, M. Kaste, C. Fieschi, D. Toni, E. Lesaffre, R. von Kummer, G. Boysen, E. Bluhmki, G. Höxter, M. Mahagne   +9 more
semanticscholar   +1 more source

Plasminogen Activators and Plasminogen Activator Inhibitors in Neural Developmenta

Annals of the New York Academy of Sciences, 1992
N W, Seeds, S, Verrall, G, Friedman, S, Hayden, D, Gadotti, S, Haffke, K, Christensen, B, Gardner, P, McGuire, A, Krystosek   +9 more
openaire   +2 more sources

The Role of Plasminogen Activator Inhibitor Type-1 in Fibrosis

Seminars in Thrombosis and Hemostasis, 2016
P. Flevaris, Douglas E. Vaughan
semanticscholar   +1 more source

The urokinase-type plasminogen activator (uPA) system as a biomarker and therapeutic target in human malignancies

Expert opinion on therapeutic targets, 2016
S. Su, Chiao-Wen Lin, Wei-En Yang, W. Fan, Shun-Fa Yang   +4 more
semanticscholar   +1 more source

PLASMJN AND PLASMINOGEN ACTIVATORS: KINETICS, AND KINETICS OF PLASMINOGEN ACTIVATION

Annals of the New York Academy of Sciences, 1981
K C, Robbins, R C, Wohl, L, Summaria
openaire   +2 more sources

t-Plasminogen Activator

2013
Lijnen, HR, Rijken, Dick
openaire   +2 more sources

ACTIVATION OF PLASMINOGEN

Annals of the New York Academy of Sciences, 1957
openaire   +2 more sources