Results 351 to 360 of about 3,530,803 (397)

Activating effect of the plasminogen activators on plasminogens of different mammalia species

Thrombosis Research, 1995
Abstract Plasmin (E.C. 3.4.21.7.) is a major serine proteolytic enzyme responsible for fibrinolytic function in mammalia blood plasma. It is formed by activation of proenzyme plasminogen with the known activators such as urokinase (UK, E.C. 3.4.21.31.), tissue-type plasminogen activator (t-PA, E.C. 3.4.21.67.) or streptokinase (SK) (1, 2).
Michail V. Rublenko, Sergey A. Yakovlev, Vitaliy I. Izdepsky, Eugeni M. Makogonenko   +3 more
openaire   +3 more sources

Lipoprotein(a) inhibition of plasminogen activation by tissue-type plasminogen activator

Thrombosis Research, 1990
Here experimental evidence is presented demonstrating that Lp(a) inhibits the activation of Pg by the physiologic activator tissue-type plasminogen activator (t-PA) bound to fibrinogen fragments. The competitive inhibition constant, Kie, of the Lp(a) inhibition is 22 nM, or 8.6 mg/dL which corresponds to normal plasma ...
Jay M. Edelberg, Mario Gonzalez-Gronow, Salvatore V. Pizzo   +2 more
openaire   +3 more sources

Kinetic studies of plasminogen activation by epithelial tissue plasminogen activator

Blood Coagulation & Fibrinolysis, 1990
Initial-rate kinetic studies of the activation of plasminogen by epithelial activator were performed in the absence and in the presence of fibrinogen and CNBr-digested fibrinogen, under assay conditions similar to those described by Hoylaerts et al. (J Biol Chem, 257, 2912, 1982).
A Electricwala, R J Ling, Atkinson T
openaire   +3 more sources

Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS)

Journal of the American Medical Association (JAMA), 1995
W. Hacke, M. Kaste, C. Fieschi, D. Toni, E. Lesaffre, R. von Kummer, G. Boysen, E. Bluhmki, G. Höxter, M. Mahagne   +9 more
semanticscholar   +1 more source

The Role of Plasminogen Activator Inhibitor Type-1 in Fibrosis

Seminars in Thrombosis and Hemostasis, 2016
P. Flevaris, Douglas E. Vaughan
semanticscholar   +1 more source

The urokinase-type plasminogen activator (uPA) system as a biomarker and therapeutic target in human malignancies

Expert opinion on therapeutic targets, 2016
S. Su, Chiao-Wen Lin, Wei-En Yang, W. Fan, Shun-Fa Yang   +4 more
semanticscholar   +1 more source

Plasminogen Activators and Plasminogen Activator Inhibitors in Neural Developmenta

Annals of the New York Academy of Sciences, 1992
Alphonse Krystosek, Susan Haffke, Nicholas W. Seeds, Steve Hayden, Paul G. McGuire, Shahla Verrall, Daniela Gadotti, Glenn C. Friedman, Kathy Christensen, Brenda Gardner   +9 more
openaire   +3 more sources

ACTIVATION OF PLASMINOGEN

Annals of the New York Academy of Sciences, 1957
openaire   +3 more sources

PLASMJN AND PLASMINOGEN ACTIVATORS: KINETICS, AND KINETICS OF PLASMINOGEN ACTIVATION

Annals of the New York Academy of Sciences, 1981
Kenneth C. Robbins, Louis Summaria, R C Wohl   +2 more
openaire   +3 more sources

Involvement of Urokinase‐Type Plasminogen Activator System in Cancer: An Overview

Medicinal research reviews (Print), 2014
Ahmed H. Mekkawy, M. Pourgholami, D. Morris   +2 more
semanticscholar   +1 more source