Results 261 to 270 of about 3,326,153 (390)

Identification of a Novel Mutation in the SERPINE1 Gene Causing Clinical Hyperfibrinolysis in English Springer Spaniel Dogs

open access: yesJournal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Background A 7‐month‐old female spayed English Springer Spaniel (ESS) was evaluated for spontaneous hemoperitoneum. Hyperfibrinolysis was identified on thromboelastography. Hypothesis/Objectives To identify a genetic mutation causing congenital hyperfibrinolysis in the proband and evaluate the prevalence of the mutation in the ESS breed ...
Kelley Kilpatrick   +7 more
wiley   +1 more source

Inhibiting the Histone Demethylase Kdm4a Restrains Cardiac Fibrosis After Myocardial Infarction by Promoting Autophagy in Premature Senescent Fibroblasts

open access: yesAdvanced Science, Volume 12, Issue 21, June 5, 2025.
Kdm4a downregulation restrains excessive cardiac interstitial fibrosis and remodeling by depressing the premature senescence of fibroblasts in the advanced stage after MI but does not affect early ventricular rupture. It verified that Kdm4a downregulation promotes autophagy in premature senescent fibroblasts by increasing the H3K9m3 modification of the
Ming Jin   +15 more
wiley   +1 more source

LC‐MS/MS proteomics identifies plasma proteins related to cognition over 9‐year follow‐up

open access: yesAlzheimer's &Dementia, Volume 21, Issue 6, June 2025.
Abstract INTRODUCTION This project identified plasma proteins predictive of cognitive decline across a robust neuropsychological protocol over a 9‐year period. METHODS Vanderbilt Memory and Aging Project participants (n = 336, 73 ± 7 years, 59% male, 87% non‐Hispanic White, 10% Black/African American) underwent blood draw for baseline plasma protein ...
Hailey A. Adegboye   +19 more
wiley   +1 more source

Intravenous Thrombolysis in Patients Taking Direct Oral Anticoagulation Treatment Before Stroke Onset: Results from the Safe Implementations of Treatments in Stroke International Stroke Registry

open access: yesAnnals of Neurology, Volume 97, Issue 6, Page 1205-1214, June 2025.
Objectives Intravenous thrombolysis (IVT) is contraindicated for acute ischemic stroke (AIS) patients taking direct oral anticoagulants (DOACs) within 48 hours before index stroke. Limited data exist on off‐label use of IVT for these patients. We compared the safety and outcomes of IVT in AIS patients with DOAC treatment and patients with no OAC before
Marius Matusevicius   +11 more
wiley   +1 more source

Basic mechanisms and regulation of fibrinolysis [PDF]

open access: yes, 2015
Kolev, Kraszimir Nikolaev   +1 more
core   +1 more source

Home - About - Disclaimer - Privacy