Results 211 to 220 of about 302,576 (367)

Treatment Failure and Post-Artesunate Delayed Haemolysis in a Returned Traveller From Uganda With Partially Drug-Resistant Severe Plasmodium falciparum Malaria. [PDF]

open access: yesMed J Aust
ABSTRACT A man aged in his 40s, recently returned from Uganda, was hospitalised with Plasmodium falciparum malaria, with hyperparasitaemia of ~1.5 × 106 parasites/μL (26%). He received intravenous artesunate followed by artemether–lumefantrine. However, parasite clearance was delayed, and despite a negative blood film following treatment, the patient ...
Travis J   +6 more
europepmc   +2 more sources

Host‐associated beneficial gut microbiota boosts induced immunity and limits immune deployment costs in bumblebees

open access: yesJournal of Animal Ecology, Volume 95, Issue 1, Page 217-229, January 2026.
Our work demonstrates a key role for host‐associated microbiota in the realization of induced immune defense, and contributes more broadly to our understanding of microbiota‐immune interactions in the context of ecological immunology. Abstract Ecological immunology posits that variation in host resistance to infection may be attributed partly to the ...
Austin C. Calhoun   +4 more
wiley   +1 more source

Harnessing controlled human infection models to accelerate vaccine development for neglected tropical diseases: Lessons from leishmaniasis

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Controlled Human Infection Models (CHIMs) offer a powerful approach to accelerate vaccine development for neglected tropical diseases (NTDs). This review highlights scientific and translational advances enabled by CHIMs, with a focus on a novel Leishmania major model.
Vivak Parkash
wiley   +1 more source

Negative Frequency‐Dependent Selection Promotes Strain Structure in a Plant Pathogen

open access: yesEcology Letters, Volume 29, Issue 1, January 2026.
Strains of the plant pathogen Pseudomonas syringae, defined by the combination of virulence factors known as effectors, exhibit in isolates from the Midwestern US a modular population structure congruent with core genome phylogeny. A stochastic and individual‐based computational model supports a role of negative frequency‐dependent selection in ...
Shuanger Li   +5 more
wiley   +1 more source

Sex in Immune Cells and Parasitic Diseases — A Complex Relationship

open access: yesImmunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Epidemiological studies consistently show that many parasitic diseases affect males more frequently than females. These disparities are multifactorial, arising partly from gender‐specific behaviors that influence exposure risk and health‐seeking practices, especially in low‐ and middle‐income countries. Increasing evidence also highlights that
Barbara Honecker   +2 more
wiley   +1 more source

CD44 cross-linking promotes Plasmodium falciparum invasion. [PDF]

open access: yesNat Commun
Kongsomboonvech AK   +7 more
europepmc   +1 more source

PoolSeq Genome‐Wide Association Studies and Microbial Signature Analyses Identify Novel Candidates Associated With Pyrethroid Resistance Evolution in Anopheles funestus in Cameroon

open access: yesMolecular Ecology, Volume 35, Issue 1, January 2026.
ABSTRACT Intensification of insecticide resistance in malaria vectors is undermining efforts to sustain control strategies. The evolutionary features underlying such exacerbation in major vector such as Anopheles funestus are only partially understood.
Mahamat Gadji   +7 more
wiley   +1 more source

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