Results 211 to 220 of about 302,576 (367)
Treatment Failure and Post-Artesunate Delayed Haemolysis in a Returned Traveller From Uganda With Partially Drug-Resistant Severe Plasmodium falciparum Malaria. [PDF]
ABSTRACT A man aged in his 40s, recently returned from Uganda, was hospitalised with Plasmodium falciparum malaria, with hyperparasitaemia of ~1.5 × 106 parasites/μL (26%). He received intravenous artesunate followed by artemether–lumefantrine. However, parasite clearance was delayed, and despite a negative blood film following treatment, the patient ...
Travis J +6 more
europepmc +2 more sources
Our work demonstrates a key role for host‐associated microbiota in the realization of induced immune defense, and contributes more broadly to our understanding of microbiota‐immune interactions in the context of ecological immunology. Abstract Ecological immunology posits that variation in host resistance to infection may be attributed partly to the ...
Austin C. Calhoun +4 more
wiley +1 more source
Controlled Human Infection Models (CHIMs) offer a powerful approach to accelerate vaccine development for neglected tropical diseases (NTDs). This review highlights scientific and translational advances enabled by CHIMs, with a focus on a novel Leishmania major model.
Vivak Parkash
wiley +1 more source
Negative Frequency‐Dependent Selection Promotes Strain Structure in a Plant Pathogen
Strains of the plant pathogen Pseudomonas syringae, defined by the combination of virulence factors known as effectors, exhibit in isolates from the Midwestern US a modular population structure congruent with core genome phylogeny. A stochastic and individual‐based computational model supports a role of negative frequency‐dependent selection in ...
Shuanger Li +5 more
wiley +1 more source
Sex in Immune Cells and Parasitic Diseases — A Complex Relationship
ABSTRACT Epidemiological studies consistently show that many parasitic diseases affect males more frequently than females. These disparities are multifactorial, arising partly from gender‐specific behaviors that influence exposure risk and health‐seeking practices, especially in low‐ and middle‐income countries. Increasing evidence also highlights that
Barbara Honecker +2 more
wiley +1 more source
CD44 cross-linking promotes Plasmodium falciparum invasion. [PDF]
Kongsomboonvech AK +7 more
europepmc +1 more source
ABSTRACT Intensification of insecticide resistance in malaria vectors is undermining efforts to sustain control strategies. The evolutionary features underlying such exacerbation in major vector such as Anopheles funestus are only partially understood.
Mahamat Gadji +7 more
wiley +1 more source
Unusual replication dynamics during Plasmodium falciparum schizogony. [PDF]
Berners-Lee R, Smith TK.
europepmc +1 more source

