Results 181 to 190 of about 68,345 (214)
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Single-cell views of the Plasmodium life cycle
Trends in Parasitology, 2022Malaria-causing Plasmodium parasites undergo multiple phenotypic transitions as they cycle between diverse niches in the mammalian and mosquito hosts. Recent applications of single-cell technologies to Plasmodium have enabled the systematic investigation of the distinct stages across the life cycle.
Real, Eliana, Mancio-Silva, Liliana
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Protein kinase 9 is not required for completion of the Plasmodium berghei life cycle
Microbiological Research, 2022Protein kinases uniquely expressed in Plasmodium represent attractive drug targets. Previous studies have reported that Plasmodium falciparum Protein kinase 9 (Pk9) phosphorylates regulatory serine 106 of the ubiquitin-conjugating enzyme (Ubc13) thereby negatively regulating its activity.
Sunil Kumar Narwal +2 more
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Plasmodium Egress Across the Parasite Life Cycle
Annual Review of Microbiology, 2022Human malaria, caused by infection with Plasmodium parasites, remains one of the most important global public health problems, with the World Health Organization reporting more than 240 million cases and 600,000 deaths annually as of 2020 ( World malaria report 2021).
Jeffrey D, Dvorin, Daniel E, Goldberg
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Plasmodium yoelii yoelii 17XNL constitutively expressing GFP throughout the life cycle [PDF]
Experimental Parasitology, 2007 Plasmodium yoelii is a rodent parasite commonly used as a model to study malaria infection. It is the preferred model parasite for liver-stage immunological studies and is also widely used to study hepatocyte, erythrocyte and mosquito infection. We have generated a P.
Takeshi, Ono +2 more
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Life-Cycle of Plasmodium Relictum Var. Matutinum
American Journal of Tropical Medicine and Hygiene, 1940Summary and Conclusions 1. Exoerythrocytic schizogony has been looked for in 18 cases of infection with Plasmodium relictum var. matutinum, and demonstrated in 9. It has been found both in blood-induced infections and those resulting from the bites of infected mosquitoes. 2.
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Melatonin Effects on Plasmodium Life Cycle: New Avenues for Therapeutic Approach
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery, 2012Malaria remains a global health problem affecting more than 515 million people all over the world including Malaysia. It is on the rise, even within unknown regions that previous to this were free of malaria. Although malaria eradication programs carried out by vector control programs are still effective, anti-malarial drugs are also used extensively ...
Venkataramanujam, Srinivasan +3 more
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DNA Repair, 2021
Mitochondrion is an essential organelle in malaria parasite and its DNA must be maintained for optimal function during its complex life cycle. Base excision repair is one of the major pathways by which this is achieved. Apurinic/apyrimidinic (AP) endonucleases are important components of this pathway as they create a nick at the 5'-phosphodiester bond ...
Pratik Narain Srivastava +2 more
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Mitochondrion is an essential organelle in malaria parasite and its DNA must be maintained for optimal function during its complex life cycle. Base excision repair is one of the major pathways by which this is achieved. Apurinic/apyrimidinic (AP) endonucleases are important components of this pathway as they create a nick at the 5'-phosphodiester bond ...
Pratik Narain Srivastava +2 more
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Life Cycle and Patterns of Development of Plasmodium berghei in Normal and Experimental Hosts
Military Medicine, 1966M, Yoeli +3 more
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Gene disruption reveals a dispensable role for Plasmepsin VII in the Plasmodium berghei life cycle
Molecular and Biochemical Parasitology, 2014Plasmepsins (PM), aspartic proteases of Plasmodium, comprises a family of ten proteins that perform critical functions in Plasmodium life cycle. Except VII and VIII, functions of the remaining plasmepsin members have been well characterized. Here, we have generated a mutant parasite lacking PM VII in Plasmodium berghei using reverse genetics approach ...
Babu S. Mastan +4 more
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