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Population dynamics of Herves transposable element in Anopheles gambiae [PDF]
, 2005 Aluvihare, C +7 more
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The cytoplasmic ribosomal RNAs of Plasmodium spp
Parasitology Today, 1995Plasmodium spp maintain several structurally distinct sets of ribosomal RNA genes whose expression is developmentally regulated. This feature sets them apart from all other eukaryotes studied to date. In this review, Thomas McCutchan, Jun Li, Glenn McConkey, John Rogers and Andy Waters give an account of the progress in our understanding of this ...
T F, McCutchan +4 more
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The isoprenoid-precursor dependence of Plasmodium spp.
Natural Product Reports, 2012Due to the increase in resistance of Plasmodium spp. against available antimalarials, there is a need for new, effective and innovative drugs. The non-mevalonate pathway for the biosynthesis of the universal isoprenoid precursors, which is absent in humans, is suggested as an attractive source of targets for such drugs with a novel mode of action.
Jan-Ytzen, van der Meer +1 more
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Action mechanisms of metallic compounds on Plasmodium spp.
Journal of Trace Elements in Medicine and Biology, 2022Malaria is a parasitic disease with the highest morbidity and mortality worldwide. Unfortunately, during the last decades, the causal agent, Plasmodium spp., has developed resistance to chloroquine and artemisinin. For this reason, metallic compounds have been proposed as an optional treatment since they have shown a potential antimalarial effect with ...
Casarrubias-Tabarez, Brenda +4 more
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Lipid compartmentalization in erythrocytes parasitized by Plasmodium spp
Parasitology Today, 1992Although reasonably well protected from the host immune system by the erythrocyte membrane, the intraerythrocytic malaria parasite has to make that membrane compatible with its own requirements for development and multiplication. The development of Plasmodium spp brings about major changes in the lipid composition of the host cell membrane, as well as ...
A P, Simões +2 more
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Iron Acquisition by Plasmodium spp
Parasitology Today, 1999The acquisition of iron by parasitic protozoa has recently been reviewed1xWilson, M.E. and Britigan, B.E. Parasitol. Today. 1998; 14: 348–353Abstract | Full Text | Full Text PDF | PubMed | Scopus (42)See all References1 and commented2xTachezy, J. Parasitol. Today. 1999; 15: 207Abstract | Full Text | Full Text PDF | PubMedSee all References2.
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Contribution of Transcriptome to Elucidate the Biology of Plasmodium spp
Current Topics in Medicinal Chemistry, 2022Abstract: In the present review, we discuss some of the new technologies that have been applied to elucidate how Plasmodium spp escape from the immune system and subvert the host physiology to orchestrate the regulation of its biological pathways.
Kleber Simônio, Parreira +3 more
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Current Treatment and Drug Discovery Against Leishmania spp. and Plasmodium spp.: A Review
Current Drug Targets, 2009Malaria and leishmaniasis are the most prevalent tropical diseases caused by protozoan parasites. Half of world's population is at risk of malaria and more than 2 million of new cases of leishmaniasis occur annually. There are no vaccines available for these diseases and current treatments suffer from several limitations.
Angela Kaysel, Cruz +6 more
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Quinolone-Based Drugs Against Toxoplasma gondii and Plasmodium spp
Current Drug Target -Infectious Disorders, 2005Owing to the rapid emergence of multi-resistant strains of Plasmodium spp. (the causative agents of malaria) and the limitations of drugs used against Toxoplasma gondii (an important opportunistic pathogen associated with AIDS and congenital birth defects), the discovery of new therapeutical targets and the development of new drugs are needed.
Guillaume, Anquetin +2 more
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