Detection ofPlasmodiumspp. in Human Feces
Emerging Infectious Diseases, 2012 Comparison of diagnostic methods for Plasmodium spp. in humans from Uganda and the Central African Republic showed that parasites can be efficiently detected by PCR in fecal samples. These results, which rely solely on PCR-based examination of feces, validate numerous estimates of the prevalence of malaria in great apes.
Milan Jirků +5 more
openaire +3 more sources
An impossible journey? The development of Plasmodium falciparum NF54 in Culex quinquefasciatus. [PDF]
PLoS ONE, 2013 Although Anopheles mosquitoes are the vectors for human Plasmodium spp., there are also other mosquito species-among them culicines (Culex spp., Aedes spp.)-present in malaria-endemic areas.
Julia Knöckel +6 more
doaj +1 more source
The evolutionary dynamics of variant antigen genes in Babesia reveal a history of genomic innovation underlying host-parasite interaction [PDF]
, 2014 Babesia spp. are tick-borne, intraerythrocytic hemoparasites that use antigenic variation to resist host immunity, through sequential modification of the parasite-derived variant erythrocyte surface antigen (VESA) expressed on the infected red blood cell
Allred, David R. +30 more
core +6 more sources
Protein import into the endosymbiotic organelles of apicomplexan parasites [PDF]
, 2018 The organelles of endosymbiotic origin, plastids, and mitochondria, evolved through the serial acquisition of endosymbionts by a host cell. These events were accompanied by gene transfer from the symbionts to the host, resulting in most of the organellar
Fellows, Justin +3 more
core +1 more source
Assessing Transmission Blockade in Plasmodium spp.
, 2012 Here we describe a series of methods that can be used to assess the activities of "vaccines," drugs, and genetically modified vectors, for their abilities to inhibit transmission of Plasmodium from its vertebrate to its mosquito hosts. The selection of method to be used is determined by the purpose of the experiment, which can include the determination
Blagborough, A +5 more
openaire +2 more sources
The primate malaria parasites Plasmodium malariae, Plasmodium brasilianum and Plasmodium ovale spp.: genomic insights into distribution, dispersal and host transitions [PDF]
Malaria Journal, 2022 AbstractDuring the twentieth century, there was an explosion in understanding of the malaria parasites infecting humans and wild primates. This was built on three main data sources: from detailed descriptive morphology, from observational histories of induced infections in captive primates, syphilis patients, prison inmates and volunteers, and from ...
Fuehrer, Hans-Peter +2 more
openaire +3 more sources
Avian malaria co-infections confound infectivity and vector competence assays of Plasmodium homopolare. [PDF]
, 2018 Currently, there are very few studies of avian malaria that investigate relationships among the host-vector-parasite triad concomitantly. In the current study, we experimentally measured the vector competence of several Culex mosquitoes for a newly ...
Barker, Christopher M +5 more
core +1 more source
Dynamic interactions ofPlasmodiumspp. with vascular endothelium [PDF]
Tissue Barriers, 2016 Plasmodial species are protozoan parasites that infect erythrocytes. As such, they are in close contact with microvascular endothelium for most of the life cycle in the mammalian host. The host-parasite interactions of this stage of the infection are responsible for the clinical manifestations of the disease that range from a mild febrile illness to ...
Mark R, Gillrie, May, Ho
openaire +2 more sources
Malaria Journal, 2017 Background Although a high genetic diversity of Plasmodium spp. circulating in great apes has been revealed recently due to non-invasive methods enabling detection in faecal samples, little is known about the actual mechanisms underlying the presence of ...
Mwanahamisi I. Mapua +8 more
doaj +1 more source
Epistatic Interactions between apolipoprotein E and hemoglobin S Genes in regulation of malaria parasitemia. [PDF]
PLoS ONE, 2013 Apolipoprotein E is a monomeric protein secreted by the liver and responsible for the transport of plasma cholesterol and triglycerides. The APOE gene encodes 3 isoforms Ɛ4, Ɛ3 and Ɛ2 with APOE Ɛ4 associated with higher plasma cholesterol levels and ...
Virginie Rougeron +8 more
doaj +1 more source