Results 1 to 10 of about 36,837 (231)

The anaemia of Plasmodium vivax malaria [PDF]

Malaria Journal, 2012
Plasmodium vivax threatens nearly half the world’s population and is a significant impediment to achievement of the millennium development goals. It is an important, but incompletely understood, cause of anaemia.
Douglas Nicholas M, Anstey Nicholas M, Buffet Pierre A, Poespoprodjo Jeanne R, Yeo Tsin W, White Nicholas J, Price Ric N   +6 more
doaj   +4 more sources

Orangutans Not Infected with Plasmodium vivax or P. cynomolgi, Indonesia

Emerging Infectious Diseases, 2009
After orangutans in Indonesia were reported as infected with Plasmodium cynomolgi and P. vivax, we conducted phylogenetic analyses of small subunit ribosomal RNA gene sequences of Plasmodium spp.
Balbir Singh, Paul Cliff Simon Divis
doaj   +1 more source

Contrasting Transmission Dynamics of Co-endemic Plasmodium vivax and P. falciparum: Implications for Malaria Control and Elimination. [PDF]

, 2015
BACKGROUND: Outside of Africa, P. falciparum and P. vivax usually coexist. In such co-endemic regions, successful malaria control programs have a greater impact on reducing falciparum malaria, resulting in P.
Rita Kusriastuti (164501), Neil Lobo, Ayleen Kosasih, Inge Sutanto (391795), Ferdinand Laihad, Leily Trianty (106253), Kusriastuti, Rita, Andreas Kusuma, Leily Trianty, Noviyanti, Rintis, Farah Coutrier, Taane G Clark, Lobo, Neil, Neil Lobo (736132), Trimarsanto, Hidayat, Clark, Taane G., Taane G. Clark (106263), Inge Sutanto, Rintis Noviyanti, Jutta Marfurt (92157), Marfurt, Jutta, Hawley, William A., Sutanto, Inge, Andreas Kusuma (736130), Ric N. Price (35538), Clark, Taane G, Price, Richard, Ayleen Kosasih (736131), Trianty, Leily, Ferdinand Laihad (80374), Kusuma, Andreas, Rita Kusriastuti, Tirta, Yusrifar K, Utami, Retno A.S., Auburn, Sarah, Jutta Marfurt, Coutrier, Farah, Hawley, William A, Rintis Noviyanti (106250), Sarah Auburn, Hidayat Trimarsanto (443615), Yusrifar K Tirta, Retno A. S. Utami (736128), Hidayat Trimarsanto, Farah Coutrier (736127), William A Hawley, Utami, Retno AS, Kosasih, Ayleen, William A. Hawley (339596), Retno A S Utami, Sarah Auburn (106239), Tirta, Yusrifar K., Laihad, Ferdinand, Yusrifar K. Tirta (736129), Price, Ric N, Ric N Price   +55 more
core   +1 more source

ama1 genes of sympatric Plasmodium vivax and P. falciparum from Venezuela differ significantly in genetic diversity and recombination frequency. [PDF]

, 2008
BACKGROUND: We present the first population genetic analysis of homologous loci from two sympatric human malaria parasite populations sharing the same human hosts, using full-length sequences of ama1 genes from Plasmodium vivax and P.
Sutherland, Colin J, Rosalynn L Ord, Adriana Tami, Tami, Adriana, Colin J Sutherland, Ord, Rosalynn L, Tami, Adriana; id_orcid   +6 more
core   +1 more source

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood, Jacinta R. Macdonald, Christian Anzenhofer, Tina S. Skinner‐Adams, Robert C. Reid, Thomas Kurz, David P. Fairlie, Katherine T. Andrews   +7 more
wiley   +1 more source

Molecular detection of drug resistant malaria in Southern Thailand

Malaria Journal, 2019
Background Drug resistance within the major malaria parasites Plasmodium vivax and Plasmodium falciparum threatens malaria control and elimination in Southeast Asia.
Chaturong Noisang, Christiane Prosser, Wieland Meyer, Waenurama Chemoh, John Ellis, Nongyao Sawangjaroen, Rogan Lee   +6 more
doaj   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

The incidence and differential seasonal patterns of Plasmodium vivax primary infections and relapses in a cohort of children in Papua New Guinea [PDF]

, 2016
Plasmodium vivax has the ability to relapse from dormant parasites in the liver weeks or months after inoculation, causing further blood-stage infection and potential onward transmission.
Ingrid Felger (92160), Schoepflin, S, Amanda Ross, Ross, A, Amanda Ross (187821), Ross, Amanda, Timinao, Lincoln, Koepfli, Cristian, Peter Siba (112258), Koepfli, C, Cristian Koepfli, Felger, Ingrid, Sonja Schoepflin, Marcel Tanner (33894), Marcel Tanner, Ingrid Felger, Ivo Mueller (46609), Timinao, L, Smith, T, Felger, I, Schoepflin, Sonja, Tanner, Marcel, Mueller, Ivo, Thomas Smith (74383), Siba, P, Lincoln Timinao (423264), Ivo Mueller, Peter Siba, Thomas Smith, Siba, Peter, Mueller, I, Tanner, M, Smith, Thomas, Sonja Schoepflin (92156), Lincoln Timinao, Cristian Koepfli (191306)   +35 more
core   +1 more source

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva, Monique Mantovani, Maria E. S. D. Lino, Aline O. Albuquerque, João H. M. da Silva, Ronaldo A. P. Nagem, Adriana L. Rojas, Geraldo R. Sartori, Eduardo Horjales, David Campbell, Otavio H. Thiemann   +10 more
wiley   +1 more source

Reduced risk of Plasmodium vivax malaria in Papua New Guinean children with Southeast Asian ovalocytosis in two cohorts and a case-control study [PDF]

, 2012
BACKGROUND: The erythrocyte polymorphism, Southeast Asian ovalocytosis (SAO) (which results from a 27-base pair deletion in the erythrocyte band 3 gene, SLC4A1Delta27) protects against cerebral malaria caused by Plasmodium falciparum; however, it is ...
Reeder, J. C., Livingstone Tavul (46297), Danielle I. Stanisic (137910), Laman Moses, Peter Siba (112258), Dabod Elijah, Laman, M, Siba, P., Zimmerman, P. A., Senn, Nicolas, Davis, TME, Nicolas Senn, J. Robinson, Leanne, Patricia Rarau (137896), Leanne J. Robinson (137914), Rarau, Patricia, Pascal Michon, Robinson Leanne J., Dabod, Elijah, Tavul, L., Laurens Manning (112248), Livingstone Tavul, Grimberg, B. T., Manning, Laurens, Aponte, JJ, Elijah Dabod (137918), Reeder John C., Moses Laman, Michon, P., Robinson, LJ, Zimmerman Peter A., Aponte John J., Lin, E., Laman, M., I. Stanisic, Danielle, Ivo Mueller (46609), Dabod, E., Senn, N, Laurens Manning, Tavul, Livingstone, John J Aponte, Enmoore Lin, Davis Timothy M. E., Michon, P, Grimberg, BT, Mueller, Ivo, Siba, P, Tavul, L, Ivo Mueller, Senn, N., Enmoore Lin (137888), Lin, Enmoore, Manning, L., King Christopher L., Leanne J Robinson, Brian T. Grimberg (137907), Stanisic Danielle I., Pascal Michon (46294), John C Reeder, Timothy M. E. Davis (112260), Robinson, L. J., Christopher L. King (137930), Rarau, P., Dabod, E, Rosanas-Urgell, Anna, Reeder, JC, Rosanas-Urgell Anna, Rosanas-Urgell, A., Aponte, J. J., T. Grimberg, Brian, Stanisic, D. I., Michon, Pascal, Davis, T. M., Rarau Patricia, John C. Reeder (137922), Lin Enmoore, Senn Nicolas, C. Reeder, John, Peter A. Zimmerman (137926), Peter Siba, Zimmerman, PA, Siba, Peter, Mueller, I, Manning, L, Brian T Grimberg, Manning Laurens, L. King, Christopher, Michon Pascal, Siba Peter, Mueller Ivo, Christopher L King, Timothy M E Davis, M. E. Davis, Timothy, Moses Laman (112250), King, CL, Laman, Moses, J. Aponte, John, Grimberg Brian T., Tavul Livingstone, Danielle I Stanisic, Elijah Dabod, Stanisic, DI, Patricia Rarau, King, C. L., Anna Rosanas-Urgell, Lin, E, Mueller, I., John J. Aponte (89761), Nicolas Senn (137902), A. Zimmerman, Peter, Anna Rosanas-Urgell (112252), Rarau, P, Peter A Zimmerman, Rosanas-Urgell, A   +113 more
core   +1 more source