Results 151 to 160 of about 151,016 (323)

Genomic Analysis of Plasmodium vivax in Southern Ethiopia Reveals Selective Pressures in Multiple Parasite Mechanisms

Journal of Infectious Diseases, 2019
The Horn of Africa harbors the largest reservoir of Plasmodium vivax in the continent. Most of sub-Saharan Africa has remained relatively vivax-free due to a high prevalence of the human Duffy-negative trait, but the emergence of strains able to invade ...
Sarah Auburn, Sisay Getachew, R. Pearson, R. Amato, Olivo Miotto, Hidayat Trimarsanto, S. Zhu, Angela Rumaseb, J. Marfurt, Rintis Noviyanti, M. Grigg, Bridget E. Barber, T. William, S. Gonçalves, Eleanor Drury, Kanlaya Sriprawat, N. Anstey, F. Nosten, B. Petros, A. Aseffa, G. McVean, D. Kwiatkowski, R. Price   +22 more
semanticscholar   +1 more source

Analysis of Global Research on Malaria and Plasmodium vivax [PDF]

, 2019
Background: Malaria is one of the infectious diseases of greatest interest to the scientific community and of greatest concern to international health authorities.
Cebrián Carmona, José, Garrido Cárdenas, José Antonio, González Cerón, Lilia, Manzano Agugliaro, Francisco, Mesa Valle, Concepción   +4 more
core   +1 more source

Prospective evaluation of artemether-lumefantrine for the treatment of non-falciparum and mixed-species malaria in Gabon [PDF]

, 2012
Background: The recommendation of artemisinin combination therapy (ACT) as first-line treatment for uncomplicated falciparum malaria is supported by a plethora of high quality clinical trials.
Adegnika, Ayola A., Basra, Arti, Bélard, Sabine, Capan, Mesküre, Diop, Daisy A., Joanny, Fanny, Kleine, Christian, Kremsner, Peter G., Kurth, Florian, Mombo-Ngoma, Ghyslain, Mordmüller, Benjamin, Ramharter, Michael, Würbel, Heike   +12 more
core   +1 more source

Targeting Bottlenecks in Malaria Transmission: Antibody‐Epitope Descriptions Guide the Design of Next‐Generation Biomedical Interventions

Immunological Reviews, Volume 330, Issue 1, March 2025.
ABSTRACT Malaria continues to pose a significant burden to global health. Thus, a strong need exists for the development of a diverse panel of intervention strategies and modalities to combat malaria and achieve elimination and eradication goals. Deploying interventions that target bottlenecks in the transmission life cycle of the causative agent of ...
Randy Yoo, Matthijs M. Jore, Jean‐Philippe Julien   +2 more
wiley   +1 more source

Association of Impaired Cytochrome P450 2D6 Activity Genotype and Phenotype With Therapeutic Efficacy of Primaquine Treatment for Latent Plasmodium vivax Malaria

JAMA Network Open, 2018
Key Points Question How is natural variation in cytochrome P450 2D6 activity associated with therapeutic efficacy of primaquine phosphate against latent Plasmodium vivax malaria?
J. Baird, M. Louisa, Rintis Noviyanti, L. Ekawati, I. Elyazar, Decy Subekti, Krisin Chand, Anggi Gayatri, Instiaty, S. Soebianto, Chelzie Crenna-Darusallam, D. Djoko, Bambang Dwi Hasto, Dubel Meriyenes, D. Wesche, E. Nelwan, I. Sutanto, H. Sudoyo, R. Setiabudy   +18 more
semanticscholar   +1 more source

Chloroquine Resistance inPlasmodium vivax [PDF]

Antimicrobial Agents and Chemotherapy, 2004
Emerging resistance to chloroquine (CQ) by Plasmodium vivax threatens the health of the hundreds of millions of people routinely exposed to the risk of infection with this organism. CQ has been the first-line therapy for vivax malaria since 1946 (32, 115). Plasmodium falciparum developed resistance to CQ in the 1950s (110), and today it occurs globally
openaire   +4 more sources

Molecular Detection of Malaria in South Punjab with Higher Proportion of Mixed Infections

Iranian Journal of Parasitology, 2014
Background: Malaria is well known for its fatalities worldwide, Plasmodium vivax and the Plasmodium falciparum are the two important species of malaria reported from Pakistan and creating lots of morbidities across the country.
Saba Shahzadi, Tanveer Akhtar, Atif Hanif, Sumrin Sahar, Sadaf Niaz, Hazrat Bilal   +5 more
doaj  

Insights into the Cytoadherence Phenomenon of Plasmodium vivax: The Putative Role of Phosphatidylserine

Frontiers in Immunology, 2017
Plasmodium vivax is the most geographically widespread and the dominant human malaria parasite in most countries outside of sub-Saharan Africa and, although it was classically recognized to cause benign infection, severe cases and deaths caused by P ...
Paulo Renato Totino, Stefanie Costa Lopes   +1 more
doaj   +1 more source

Long-term sustained malaria control leads to inbreeding and fragmentation of Plasmodium vivax populations [PDF]

arXiv, 2016
Plasmodium vivax populations are more resistant to malaria control strategies than Plasmodium falciparum, maintaining high genetic diversity and gene flow even at low transmission. To quantify the impact of declining transmission on P. vivax populations, we investigated population genetic structure over time during intensified control efforts and over ...
arxiv  

Prevalence and Associated Factors of Schistosoma mansoni and Other Intestinal Helminthes Co‐Infection Among Malaria Positive Patients in Malaria Endemic Areas of Northeast, Ethiopia: A Cross‐Sectional Study

Health Science Reports, Volume 8, Issue 2, February 2025.
ABSTRACT Background and Aims Schistosoma mansoni and malaria share a similar epidemiological distribution or co‐endemicity. Co‐infection are a global public health burden where epidemiological evidence is crucial to taking evidence‐based intervention. Thus, the aim of this study was to assess the prevalence and associated factors of Schistosoma mansoni
Yeshi Metaferia, Abdurahaman Seid, Genet Molla Fenta, Daniel Gebretsadik Weldehanna, Aderaw Adamu, Alemu Gedefie   +5 more
wiley   +1 more source