Results 171 to 180 of about 151,016 (323)

In silico comparative genomics analysis of Plasmodium falciparum for the identification of putative essential genes and therapeutic candidates.

open access: yes, 2014
A sequence of computational methods was used for predicting novel drug targets against drug resistant malaria parasite Plasmodium falciparum. Comparative genomics, orthologous protein analysis among same and other malaria parasites and protein-protein ...
Altschul   +45 more
core   +1 more source

Plasmodium vivax Malaria Viewed through the Lens of an Eradicated European Strain

open access: yesbioRxiv, 2019
The protozoan Plasmodium vivax is responsible for 42% of all cases of malaria outside Africa. The parasite is currently largely restricted to tropical and subtropical latitudes in Asia, Oceania and the Americas.
L. van Dorp   +17 more
semanticscholar   +1 more source

Sign Epistasis and the Geometry of Interactions [PDF]

open access: yesarXiv, 2018
Approaches to gene interactions based on sign epistasis have been highly influential in recent time. Sign epistasis is useful for relating local and global properties of fitness landscapes, as well as for analyzing evolutionary trajectories and constraints.
arxiv  

Epidemiology, drug resistance, and pathophysiology of Plasmodium vivax malaria

open access: yesJournal of Vector Borne Diseases, 2018
Malaria, caused by the protozoan parasites of the genus Plasmodium, is a major health problem in many countries of the world. Five parasite species namely, Plasmodium falciparum, P. vivax, P. malariae, P. ovale, and P.
DChanne Gowda   +2 more
semanticscholar   +1 more source

Steering plasmodium with light: Dynamical programming of Physarum machine [PDF]

open access: yesarXiv, 2009
A plasmodium of Physarum polycephalum is a very large cell visible by unaided eye. The plasmodium is capable for distributed sensing, parallel information processing, and decentralized optimization. It is an ideal substrate for future and emerging bio-computing devices.
arxiv  

Plasmodium vivax Reticulocyte Binding Proteins for invasion into reticulocytes

open access: yesCellular Microbiology, 2019
Plasmodium vivax is responsible for most of the malaria infections outside Africa and is currently the predominant malaria parasite in countries under elimination programs. P. vivax preferentially enters young red cells called reticulocytes.
L. Chan   +3 more
semanticscholar   +1 more source

Plasmodium vivax malaria: Is it actually benign?

open access: yesJournal of Infection and Public Health, 2011
Plasmodium vivax (Pv) malaria is being increasingly recognized as a cause of severe malaria in children.To describe the various severe manifestations associated with vivax malaria by retrospective analysis of records.Children between the ages of 0 and 18 years with a confirmed diagnosis of Pv malaria monoinfection done by peripheral blood film (PBF ...
Bimbadarh Rath   +3 more
openaire   +4 more sources

Clinical utility of tafenoquine in the prevention of relapse of Plasmodium vivax malaria: a review on the mode of action and emerging trial data

open access: yesInfection and Drug Resistance, 2019
Tafenoquine is an 8-aminoquinoline with activity against all human life cycle stages of Plasmodium vivax, including dormant liver stages – so called hypnozoites. Its long half-life of ~15 days is allowing for a single exposure regimen.
A. B. Hounkpatin   +2 more
semanticscholar   +1 more source

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