Results 131 to 140 of about 2,702,951 (306)

Indoor Plastic Sealing Device for Well Logging Cable in Injection Well

open access: yesShiyou jixie, 2019
There are a large number of cable connectors in the pre-wired intelligent separate layer water injection string. The poor sealing of the logging cable connector seriously affects the production efficiency of the entire well logging system for injection ...
Ren Fushen   +5 more
doaj  

Multicomponent Peptide‐MXene‐Hyaluronic Acid Hydrogel as a Conductive Scaffold for Enhanced Fibroblast Proliferation and Migration Under Electrical Stimulation

open access: yesAdvanced Healthcare Materials, EarlyView.
An electrically conductive FmocFF/MXene/hyaluronic acid hydrogel combines extracellular matrix‐like architecture, self‐healing behavior, oxidation‐resistant conductivity, and biochemical cues in a single scaffold. By enabling physiologically relevant electrical stimulation, the platform enhances fibroblast attachment, proliferation, and migration ...
Offir Loboda   +7 more
wiley   +1 more source

Mechanically Compliant, Precision‐Porous Brain Implants Reduce the Foreign Body Reaction and Guide Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
This study explores how the brain responds to implants of different properties. Hydrogels with various mechanical properties and pore sizes were implanted in adult rat brains. It is observed that hydrogels with mechanical property closely matched to the brain and 40 µm pore size elicit a pro‐healing response from the brain by modulating the immune ...
Ian Dryg   +8 more
wiley   +1 more source

Mechanotransduction of Magnetically Applied Forces Leads to Mechanical Stiffening of Platelet‐Rich Plugs

open access: yesAdvanced Healthcare Materials, EarlyView.
A microfluidic device with magnetic microposts was used to assess platelet mechanobiology. The oscillatory actuation of posts with embedded iron particles was dampened by the dynamic stiffening of the platelet‐rich plugs. This stiffening process increased with applied load, but inhibiting platelet activation (ASA) or myosin contractility (blebbistatin)
Nikita Taparia   +4 more
wiley   +1 more source

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

open access: yesAdvanced Healthcare Materials, EarlyView.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim   +9 more
wiley   +1 more source

Oxygels: Tunable Phosphorescent Hydrogels for Cherenkov‐Excited Luminescence Imaging (CELI) of Oxygen

open access: yesAdvanced Healthcare Materials, EarlyView.
Biocompatible hydrogels with covalently embedded near‐infrared phosphorescent probes enable local tissue pO2 quantification by means of Cherenkov‐excited luminescence imaging (CELI), where optical excitation occurs within tissues upon irradiation with high‐energy electron beams.
Simin Belali   +7 more
wiley   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave   +8 more
wiley   +1 more source

Spatially Controlled Embedded Bioprinting of Prevascularized Spheroids‐Containing Biopatch Enables Functional Skin Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn   +6 more
wiley   +1 more source

Biphasic Co‐Delivery of Curcumin and 5‐FU using 3D‐Printed Dissolving Microneedles for Skin Cancer Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
Using pixel‐aware digital light processing, the authors created high‐resolution, dissolvable microneedles from a PEGDA/VP matrix. These microneedles encapsulate curcumin and 5‐fluorouracil and dissolve in the skin, co‐delivering drugs directly to tumours.
Rutuja N. Meshram, Dimitrios A. Lamprou
wiley   +1 more source

Multiwavelength Implantable Oximeter for Wireless Monitoring of Tissue Oxygenation in the Presence of Blood Volume Changes

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents an implantable, wireless, battery‐free oximeter that can continuously monitor physiologically consistent regional tissue oxygenation under dynamic changes of blood volume. This is achieved through multiwavelength photoplethysmography and validated both via Monte Carlo simulations and in vivo rat studies. Different stress events were
Anat Usatinsky   +12 more
wiley   +1 more source

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