Results 31 to 40 of about 165,093 (264)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Application of High-frequency Ultrasound for Detection and Characterization of Dermal Fillers in the Periorbital Region

Plastic and Reconstructive Surgery, Global Open
Background:. We aimed to compare the location and depth of multiple dermal fillers used for periorbital rejuvenation using high-frequency ultrasound and to access the resulting complications. Methods:.
Ziming Zhang, MM, Ying Jia, MD, Tulepaer Tawulan, MM, Jun Zhuang, MM, Xueshang Su, MM, Hongli Chai, MD, Jintian Hu, MD   +6 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Texturing Technologies for Plastics Injection Molding: A Review

Micromachines, 2022
Texturing is an engineering technology that can be used to enable surface functionalization in the plastics injection molding industry. A texture is defined as the geometrical modification of the topography by addition of surface features that are characterized by a smaller scale than the overall surface dimensions.
Davide Masato, Leonardo Piccolo, Giovanni Lucchetta, Marco Sorgato   +3 more
openaire   +3 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Analysis of the Pathogen Distribution and Antimicrobial Resistance after Plastic Surgery of the Urogenital System

Plastic and Reconstructive Surgery, Global Open
Background:. We aimed to summarize the distribution of pathogenic bacteria for postoperative infection of different genitourinary plastic surgery and the antimicrobial resistance of the major pathogens. Methods:.
Fengli Jiang, MM, Qi Chen, BM, Yuanyuan Wu, MM, Jinhao Lin, BM, Xueshang Su, MM, Jun Zhuang, MM, Sien Zhan, MD   +6 more
doaj   +1 more source

Development of a Material for Manufacturing a Mold for Plastic Injection [PDF]

Materials Research, 2017
قولبة الحقن هي عملية تستخدم لتصنيع كميات كبيرة من الحاويات البلاستيكية ذات الأشكال الهندسية المعقدة. على الرغم من استخدام CuBe دائمًا، إلا أن هناك حاليًا بعض السبائك البديلة مثل سبيكة CuNiSiCr التي تتميز بتكلفة تصنيع أقل وخصائص مماثلة. الهدف من هذه الورقة هو توصيف عملية الاندماج والمعالجات الميكانيكية الحرارية لسبيكة CuNiSiCr، من خلال تقنيات الفحص ...
Alfredo Carlos González, Ernesto Gustavo Maffia   +1 more
openaire   +5 more sources

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Microannulus Formation Mechanism at the Cementing Interface of a Thermal Recovery Well during Cyclic Steam Injection

Advances in Civil Engineering, 2020
During the thermal recovery of heavy oil when using cyclic steam injection technology, a microannulus tends to form at the cementing interface subjected to high temperature and pressure during steam injection, and large temperature and pressure ...
JiWei Wu, XueGang Wang, Lin Song, ShouMing Zhong, WenFeng Yin   +4 more
doaj   +1 more source