Results 211 to 220 of about 1,213,504 (244)

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

Mapping the Application of Welding Technologies in Remanufacturing of Molds and Dies. [PDF]

Materials (Basel)
Grabarski M, Medeiros BB, Pintaude G.
europepmc   +1 more source

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

Influence of Draft Angle Design on Surface Texture-Dimensional Accuracy Coupling in Injection-Molded Commodity and Engineering Polymers with Semi-Crystalline and Amorphous Characteristics. [PDF]

Polymers (Basel)
Chen HL, Huang PW, Huang YS.
europepmc   +1 more source

SIRT7‐Mediated H2BK120 Succinylation Drives Aberrant Mitophagy in Sepsis‐Associated Cognitive Dysfunction

Advanced Science, EarlyView.
Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng, Jiateng Zhou, Xiaoyu Guo, Ting Hong, Xuelian Li, Xingyu Wei, Chanhua Zhang, Xixue Zhang, Songbin Liu, Yulin Zhang, Liangfang Yao, Lina Huang, Weidong Gu   +12 more
wiley   +1 more source

Toward Compostable Packaging: Biodegradable Polymer Blends with Biobased Components for Household Chemical Bottle-Layer Applications. [PDF]

ACS Omega
Kowalczyk S, Szewczyk-Łagodzińska M, Dębowski M, Iuliano A, Truskolaska M, Krywult-Pawlik M, Jędrzejczak G, Grochowska N, Plichta A.   +8 more
europepmc   +1 more source

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source

Impact of EVOH, Ormocer^® Coating, and Printed Labels on the Recyclability of Polypropylene for Packaging Applications. [PDF]

Polymers (Basel)
Schmiedt R, Krainz M, Tosic K, Sharbafian F, Krauter S, Krauter V, Novak M, Rainer B, Washüttl M, Apprich S.   +9 more
europepmc   +1 more source

Exploring the effect of higher loading of short carbon fibers on mechanical and physico - mechanical characterization of polyamide66 and polytetrafluroethylene blend composites. [PDF]

Sci Rep
Sandeep MP, Rudresh BM, Kumar MKP, Kumar MRP, Lingesh BV, Naik NCK, Emma AF.   +6 more
europepmc   +1 more source

Robust intelligent modeling for developing an optimal predictive model of metal powder injection molded dental braces using fuzzy-logic-based multi-objective design. [PDF]

Sci Prog
Huang WT, Huang SC, Guo SH, Lin YT.
europepmc   +1 more source