Results 41 to 50 of about 10,064 (313)

Exploring an Alternative to mRNA Vaccine Cold Chain Storage: MRNA‐Lipid Nanoparticle Stability When Dried in a Polymer Matrix

Advanced Functional Materials, EarlyView.
The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett, Shahad K. Alsaiari, John L. Daristotle, Timothy A. Forster, Alicia Lau, Dhruv Varshney, Rania Afaneh, Andrew R. Hanna, Charles Sloane, David Mankus, Haitao Yu, Jiali Zhai, DongSoo Yun, Lisa H. Tostanoski, Abigail Lytton‐Jean, Dan H. Barouch, Charlotte E. Conn, Robert Langer, Ana Jaklenec, Calum J. Drummond   +19 more
wiley   +1 more source

Effect of injection parameters on mechanical and physical properties of super ultra-thin wall propylene packaging by Taguchi method

Results in Physics, 2018
The parameters of the plastic injection molding process have been investigated for the manufacture of a 64 oz. ultra-thin polypropylene bucket. The 3 main parameters, such as injection speed, melting temperature, holding pressure, were investigated to ...
Thatchanok Ginghtong, Natthapon Nakpathomkun, Chiravoot Pechyen   +2 more
doaj   +1 more source

Simulated annealing based simulation method for minimizing electricity cost considering production line scheduling including injection molding machines

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2020
While the price of electricity in Japan is increasing continuously, the plastic industry consumes considerable electric power for injection molding. The cost of electricity must be reduced to maintain product prices. Some strategies have been proposed to
Masaki ISHIHARA, Hironori HIBINO, Taku HARADA   +2 more
doaj   +1 more source

Engineering Pendant Group Chemistry to Control Hydrophilicity and Oxidative Degradation of Thioketal‐Based Biomaterials

Advanced Functional Materials, EarlyView.
Thioketal (TK) polymers are promising biomaterials due to their selective biodegradation by reactive oxygen species (ROS), but they respond slowly to physiologic doses of ROS. Here, the TK bond's pendant groups are modified to enhance the degradation of TK‐based implants both in vitro and in vivo.
Karina A. Bruce, Dylan W. Marques, Alan J. Fullenkamp, Emma‐Louise Lowell, Rais B. Fataki, Jake D. Ryan, John R. Martin   +6 more
wiley   +1 more source

Numerical Simulation of Microcellular Injection Molding: A Case Study

Annals of "Dunarea de Jos" University of Galati, Fascicle XII, Welding Equipment and Technology
The microcellular injection molding, often referred to as MuCell®, is an innovative polymer processing technique that utilizes supercritical inert gases, such as CO2 or N2, to manufacture lightweight plastic products.
A. Chaabene, A. Ben Khalifa, S. Chatti
doaj   +1 more source

Micro-Injection Moulding Of Three-Dimensional Integrated Microfluidic Devices [PDF]

, 2009
This thesis investigates the use of micro-injection moulding (μIM), as a high-volume process, for producing three-dimensional, integrated microfluidic devices.
Attia, Usama M.
core  

An evaluation of process-parameter and part-geometry effects on the quality of filling in micro-injection moulding [PDF]

, 2009
This paper addresses the use of micro-injection moulding for the fabrication of polymeric parts with microfeatures. Five separate parts with different micro- feature designs are moulded of Polymethylmethacrylate.
Alcock, Jeffrey R., Attia, Usama M.
core   +1 more source

Microfabricated Anisotropic Myobundles for the Scalable Production of Cardiac Tissue Grafts

Advanced Functional Materials, EarlyView.
Controlling the anisotropy of cardiac tissue remains an outstanding challenge in the field of cardiac tissue engineering. Here, we introduce an approach to generate anisotropic cardiac myobundles using cell‐adhesive, synthetic, electrospun fibers and stem cell‐derived cardiac fibroblasts.
Maggie E. Jewett, Javiera Jilberto, Margaret E. Stanley, David O. Ntim, Siddhi M. Bhirud, Avianna T. Schroeder, Gonzola X. Anyosa Galvez, Jingyi Xia, Samuel J. DePalma, Emmanouil Agrafiotis, Susan S. Xi, Amanda S. Bluem, Courtney M. Lestock, Adam S. Helms, David A. Nordsletten, Brendon M. Baker   +15 more
wiley   +1 more source

Dimensional accuracy control for complex components of high-strength titanium alloys by metal injection molding

Fenmo yejin jishu
High-strength titanium alloy hinge components with complex geometry were fabricated by metal injection molding (MIM). The dimensional characteristics of these components were systematically evaluated under various processing conditions by optical and ...
NIE Yifan, CAO Fulong, WEI Jinghao, LIU Chang, HAN Longxiao, LIN Yixu, CHEN Gang, WU Junwen, ZHU Minglu, QIN Mingli, QU Xuanhui   +10 more
doaj   +1 more source

Characterization of shrinkage effects in micro-injection moulding (µ-IM) [PDF]

, 2013
This thesis characterizes the effects on shrinkage in microinjection moulding. The literature review considers four branches of investigation (material properties, processing parameters, mould design and specimen design).
Annicchiarico, Daniele
core