Results 101 to 110 of about 24,053 (253)

Matsupexole: A novel nonergot dopamine receptor agonist with sustained efficacy in a rat model of Parkinson's disease and limited off‐target activity

British Journal of Pharmacology, EarlyView.
Background and Purpose Dopamine receptor agonists, particularly targeting the dopamine D2L receptor (D2LR), have been used to treat Parkinson's disease (PD). However, valvular heart disease and somnolence, mainly caused by activating the serotonin 5‐HT2B receptor (5‐HT2BR) and dopamine D3 receptor (D3R), respectively, currently challenge their clinical
Takayuki Suzuki, Fumiki Oana, Masaki Oota, Yuma Handa, Osamu Kaminuma   +4 more
wiley   +1 more source

Model-based Design Evaluation of a Compact, High-Efficiency Neutron Scatter Camera

, 2017
This paper presents the model-based design and evaluation of an instrument that estimates incident neutron direction using the kinematics of neutron scattering by hydrogen-1 nuclei in an organic scintillator.
Brubaker, Erik, Mattingly, John, Steele, John, Weinfurther, Kyle   +3 more
core   +1 more source

The effect of environmental factors on transepithelial potential in a model Amazonian teleost, the tambaqui (Colossoma macropomum): Implications for sodium balance in harsh environments

Journal of Fish Biology, EarlyView.
Abstract The tambaqui (Colossoma macropomum, G. Cuvier 1818) thrives both in the ion‐poor waters of the Amazon and in commercial aquaculture. In both, environmental conditions can be harsh due to low ion levels, occasional high salt challenges (in aquaculture), low pH, extreme PO2 levels (hypoxia and hyperoxia), high PCO2 levels (hypercapnia), high ...
Chris M. Wood, Anne Crémazy, Carolyn Morris, Ora E. Johannsson, Gudrun De Boeck, Adalberto Luis Val   +5 more
wiley   +1 more source

Radiation-resistant plastic scintillators

Nuclear Physics and Atomic Energy
Fluorinederivatives of 4'-phenyl-3-hydroxyflavone have been synthesized and used as activators for radiation-resistant plastic scintillators based on polystyrene. Plastic scintillators containing 1.0 wt. % of the corresponding activators were created.
D. A. Yelisieiev, O. V. Yelisieieva, Yu. О. Нurkalenko, P. М. Zhmurin, V. D. Alekseev, R. P. Svoiakov   +5 more
openaire   +1 more source

A new anti-neutrino detection technique based on positronium tagging with plastic scintillators

, 2015
The main signature for anti-neutrino detection in reactor and geo-neutrino experiments based on scintillators is provided by the space-time coincidence of positron and neutron produced in the Inverse Beta Decay reaction.
Consolati, G., Franco, D., Jollet, C., Meregaglia, A., Minotti, A., Perasso, S., Tonazzo, A.   +6 more
core   +3 more sources

Oxygen consumption from air and water, ammonia and urea‐N excretion, and Na+ fluxes during progressive aquatic hypoxia in Amazonian armoured catfish Pterygoplichthys gibbiceps and Pterygoplichthys pardalis

Journal of Fish Biology, EarlyView.
Abstract The Amazonian loricariid fish Pterygoplichthys gibbiceps, from the Rio Negro, and Pterygoplichthys pardalis, from the Rio Solimões, are facultative air‐breathers that can use the stomach as an air‐breathing organ. Measurement of oxygen uptake under progressive aquatic hypoxia revealed a relatively high hypoxia resistance of both species.
Bernd Pelster, Chris M. Wood, Adalberto Luis Val   +2 more
wiley   +1 more source

Characterization and performance evaluation of epoxy-based plastic scintillators for gamma ray detection

Frontiers in Physics
This research investigates the fabrication and analysis of plastic scintillators using an epoxy matrix. Plastic scintillators are widely used in radiation detection because of their low cost, ease of fabrication, resistance to moisture, and rapid decay ...
Marliyadi Pancoko, Marliyadi Pancoko, Hafni L. Nuri, Andjar Prasetyo, Azwar Manaf, Abdul Jami, Ausatha R. Yanto, Kasmudin, Utomo, Rony Djokorayono, Achmad Suntoro   +10 more
doaj   +1 more source

Sampling calorimeter to measure the photon’s incident angle [PDF]

EPJ Web of Conferences
A three-dimensional fine-segmented sampling calorimeter enables us to measure the profiles of generated shower particles along the photon’s direction. For a feasibility study, a toy detector was designed via Geant4 simulation.
Lim GeiYoub, Abe Ryota, Ahn JungKeun, Ji Su-Jeong, Kim Chong, Kim Eun-Joo, Kim Junlee, Kim YoungJun, Kim YoungJun, Kotera Katsushige, Lim Sanghoon, Naito Taichi, Park JeongWoo, Shiomi Koji, Tajima Yasuhisa, Yang Seongbae, Yoshida Hiroshi   +16 more
doaj   +1 more source

A solenoidal electron spectrometer for a precision measurement of the neutron $\beta$-asymmetry with ultracold neutrons

, 2008
We describe an electron spectrometer designed for a precision measurement of the neutron $\beta$-asymmetry with spin-polarized ultracold neutrons. The spectrometer consists of a 1.0-Tesla solenoidal field with two identical multiwire proportional chamber
Abele, Abele, Abele, B. Plaster, B. Tipton, B.W. Filippone, Czarnecki, D. Harrison, Gardner, Hardy, Hardy, Ito, J. Hsiao, J. Liu, J. Yuan, J.W. Martin, Jackson, Jackson, Marciano, Martin, Martin, Morris, Nico, R. Carr, Saunders, Schumann, Severijns, T.M. Ito, Tabata, Wilkinson   +29 more
core   +1 more source

Joint effects of elevated copper and temperature in juvenile Tambaqui exposed in black and white waters of the Amazon

Journal of Fish Biology, EarlyView.
Abstract This study aimed to investigate how exposure to elevated water temperature and metal concentration jointly affect the physiology of Amazonian fish. Aboard a research vessel in the Amazon, we evaluated the effects of water temperature (river T°C at 31.5°C and a + 4°C increase to 35.5°C) and of 3‐h copper (Cu) exposure (up to 600 μg/L) in ...
Anne Crémazy, Carolyn Morris, Susana Braz‐Mota, Chris M. Wood, Rafael M. Duarte, Ora E. Johannsson, Adalberto L. Val   +6 more
wiley   +1 more source