Results 21 to 30 of about 265,832 (311)

Pilot Study: Innovative Minimally Invasive Tarsal Tunnel Release for Diabetic Foot Ulcer Patients Minimizing Drawbacks

Plastic and Reconstructive Surgery, Global Open
Background:. Diabetic foot ulcers are challenging to manage due to the multifactorial nature of the disease, with diabetic neuropathy being a primary contributing factor.
Hian Kim Erica Ngiam, MBBS, MRCS, Wenxian Png, MBBS, MMed (Ortho), MRCSEd, FRCSEd (Ortho), Eric Wei Liang Cher, MD, MRCS, MMed (Ortho), FRCSEd (Ortho), Jack Kian Ch’ng, MBBS, MRCS, FRCS, Allen Wei Jiat Wong, MBBS, MRCS, MMed, FAMS (Plastic Surgery), Yee Onn Kok, MBBS, MRCS, MMed, FAMS (Plastic Surgery), Jiajun Feng, MD, MRCS, MMED (Surgery), FAMS (Plastic Surgery)   +6 more
doaj   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Consensus of Chinese Experts on Neck Injection Aesthetics (2024 Edition)

Xiehe Yixue Zazhi
Neck injection aesthetic, a commonly performed clinical procedure, is still lacking in comprehensive guidelines or consensus. This expert consensus is co-authored by experts from the Injection Aesthetics of the National Quality Control Center of Plastic ...
Professional Panel on Injection Aesthetics, National Quality Control Center for Plastic and Aesthetic Surgery
doaj   +1 more source

Plastic Surgery [PDF]

Journal of the Royal Army Medical Corps, 2004
The range of casualties treated by the Defence Medical Services in the recent Gulf conflict has reaffirmed the important role of plastic surgery within the military. This review seeks to highlight some areas of recent innovation and improvement within the realms of plastic surgery generally, of which some, such as the introduction of Flammacerium and ...
openaire   +2 more sources

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Under the knife: Unfavorable perceptions of women who seek plastic surgery.

PLoS ONE, 2021
Plastic surgery is growing in popularity. Despite this, there has been little exploration to date regarding the psychosocial consequences of seeking plastic surgery. Our study investigated how women seeking plastic surgery are perceived by others.
Sarah Bonell, Sean C Murphy, Scott Griffiths   +2 more
doaj   +1 more source

PLASTIC SURGERY. [PDF]

JAMA: The Journal of the American Medical Association, 1896
n ...
openaire   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source