PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source
RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis
Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao +28 more
wiley +1 more source
Global Perspectives in Plastic Surgery: View of Plastic Surgeons From Ecuador. [PDF]
Rai P, Álvarez E, Gosain AK.
europepmc +1 more source
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim +6 more
wiley +1 more source
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong +6 more
wiley +1 more source
Global Perspectives in Plastic Surgery: View of Plastic Surgeons From Vietnam. [PDF]
Rodriguez GC +4 more
europepmc +1 more source
Professional Outcomes Following The Aesthetic Society-Endorsed Aesthetic Surgery Fellowships: A Single Program Fellowship Review and National Survey. [PDF]
Thota B +5 more
europepmc +1 more source
Coexisting in a Crowded Field: A 10-year Comparison of Procedural Volumes of Plastic Surgeons and Other Surgical Specialties in the United States. [PDF]
MacKenzie EL +3 more
europepmc +1 more source
Integrating Point-of-Care Ultrasound (PoCUS) in Plastic Surgery at an Academic-Community Hospital: Enhancing Patient Care and Resource Allocation. [PDF]
Ramji M +3 more
europepmc +1 more source
Cosmetic Medicine and Aesthetic Surgery Journal: The Beautiful Bond Between Noninvasive Aesthetic Medicine and Plastic Surgery. [PDF]
Few JW, Shridharani SM.
europepmc +1 more source

