Results 61 to 70 of about 245,125 (334)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Graduate perception of cosmetic surgery training in plastic surgery residency and fellowship programs

Archives of Plastic Surgery, 2020
Background As the demand for cosmetic surgery continues to rise, plastic surgery programs and the training core curriculum have evolved to reflect these changes.
Ledibabari Mildred Ngaage, Cecelia J Kim, Chelsea Harris, Colton HL McNichols, Chinezimuzo Ihenatu, Carly Rosen, Adekunle Elegbede, Selim Gebran, Fan Liang, Erin M Rada, Arthur Nam, Sheri Slezak, Scott D Lifchez, Yvonne M Rasko   +13 more
doaj   +1 more source

A brief history of plastic surgery [PDF]

, 2012
Historically, plastic surgery have been practiced for thousands of years, going back to more primitive methods that were seen in India since around 800 B.C.
Bilokon, N.O.
core  

Disparities in Aesthetic Procedures Performed by Plastic Surgery Residents [PDF]

Aesthetic Surgery Journal, 2016
Operative experience in aesthetic surgery is an important issue affecting plastic surgery residents.This study addresses the variability of aesthetic surgery experience during plastic surgery residency.National operative case logs of chief residents in independent/combined and integrated plastic surgery residency programs were analyzed (2011-2015 ...
Jason, Silvestre, Joseph M, Serletti, Benjamin, Chang   +2 more
openaire   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Celebrity worship and incidence of elective cosmetic surgery: evidence of a link among young adults. [PDF]

, 2011
Purpose: The purpose of the current study was to explore among young adults whether celebrity worship predicted the incidence of elective cosmetic surgery within the period of 8 months after controlling for several known predictors of elective cosmetic
Day, Liza, Maltby, J
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Robotic harvest of a right gastroepiploic lymph node flap [PDF]

, 2016
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/ licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any ...
Araki, J, Chen, H. c., Ciudad, P, Date, S, Lee, Mh, LO TORTO, Federico, Nicoli, Federico   +6 more
core   +4 more sources

Multimodal Analgesia in the Aesthetic Plastic Surgery: Concepts and Strategies

Plastic and Reconstructive Surgery, Global Open, 2022
Background:. Postoperative pain management is crucial for aesthetic plastic surgery procedures. Poorly controlled postoperative pain results in negative physiologic effects and can affect length of stay and patient satisfaction.
Anna R. Schoenbrunner, MD, MAS, Girish P. Joshi, MBBS, MD, FFARCSI, Jeffrey E. Janis, MD   +2 more
doaj   +1 more source