Results 61 to 70 of about 3,613,968 (302)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Graduate perception of cosmetic surgery training in plastic surgery residency and fellowship programs

Archives of Plastic Surgery, 2020
Background As the demand for cosmetic surgery continues to rise, plastic surgery programs and the training core curriculum have evolved to reflect these changes.
Ledibabari Mildred Ngaage, Cecelia J Kim, Chelsea Harris, Colton HL McNichols, Chinezimuzo Ihenatu, Carly Rosen, Adekunle Elegbede, Selim Gebran, Fan Liang, Erin M Rada, Arthur Nam, Sheri Slezak, Scott D Lifchez, Yvonne M Rasko   +13 more
doaj   +1 more source

Antibiotic Prophylaxis in Plastic Surgery: From Systematic Review to Operative Algorithm [PDF]

, 2022
We aimed to provide a single, viable and user-friendly operative protocol for preoperative antibiotic prophylaxis that meets the needs of all plastic surgery ...
Scortecci, Leonardo, Messana, Francesco, Vindigni, Vincenzo, Brambullo, Tito, Biffoli, Bernardo, Bassetto, Franco   +5 more
core   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Evolving Trends and Practice in Plastic Surgery in a Resource-constrained Setting: A 27-year Review From Nepal

Plastic and Reconstructive Surgery, Global Open
Background:. Plastic surgery in low- and middle-income countries (LMICs) has expanded during the past decades, but data reflecting trends and practices in plastic surgery in LMICs are scarce. This study reviewed trends and practice patterns in an LMIC to
Anup Thapa, MBBS, MS, Prajjwol Luitel, MBBS, Sujan Paudel, MBBS, Sadmarg Thakur, MBBS, Aron Shrestha, MBBS, Samit Sharma, MBBS, MS, MCh, Sangam Rayamajhi, MBBS, MS, MCh, Jayan Man Shrestha, MBBS, MS, FCPS, Ishwar Lohani, MBBS, MS, MCh   +8 more
doaj   +1 more source

A Comment on: “Lip reconstruction using superficial flaps: functional and aesthetic integration” [PDF]

Surgical & Cosmetic Dermatology
This Letter to the Editor comments on the article “Lip reconstruction using superficial flaps: functional and aesthetic integration.” The reported case series provides valuable clinical examples of individualized superficial flap selection for upper and ...
Muhammed Said Aydin, Gökay Özler
doaj   +1 more source

COVID Pandemic Aftermath: Changing Dynamics on Cosmetic and Aesthetic Surgery Demands

, 2023
BACKGROUND: After the WHO's announcement of the pandemic, the quarantine process started in the country. Suspension of elective surgeries was part of these measures.
Ugur Deniz Balci, Balci, Ugur Deniz, Ercan Karacaoglu, Aktas, Ecem Hazal, Karacaoglu, Ercan, Ecem Hazal Aktas   +5 more
core   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Myostatin/Smad3 in Spinal Muscular Atrophy: Biomarkers of Disease Severity and Treatment Response

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Given the role of Myostatin (MSTN) in muscle homeostasis and its modulation by current spinal muscular atrophy (SMA) therapies, we investigated serum MSTN and, for the first time, its downstream effector Smad3 as candidate non‐invasive biomarkers in SMA patients undergoing disease‐modifying therapies (DMTs).
Giorgia Riolo, Claudia Dosi, Stefano Parravicini, Riccardo Zanin, Marta Cheli, Eleonora Giacopuzzi Grigoli, Amalia Canciello, Francesca Andreetta, Riccardo Masson, Silvia Bonanno, Stefania Marcuzzo, Lorenzo Maggi   +11 more
wiley   +1 more source

The Importance of Plastic Surgery in Multidisciplinary Teams: A Systematic Review and Meta-analysis of Comparative Studies

Plastic and Reconstructive Surgery, Global Open
Background:. Multidisciplinary team (MDT) care facilitates coordinated expertise that leads to improved patient safety and outcomes. Yet, no prior study has quantified reported benefits from plastic surgery–inclusive MDTs across several procedures.
Abdulaziz Elemosho, MD, Ramiz Kardan, MD, Edward M. Reece, MD, FACS, Jason M. Souza, MD, FACS, Chad Gordon, DO, B. Todd Heniford, MD, FACS, Jeffrey E. Janis, MD, FACS   +6 more
doaj   +1 more source