Results 61 to 70 of about 249,070 (307)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Evolving Trends and Practice in Plastic Surgery in a Resource-constrained Setting: A 27-year Review From Nepal

Plastic and Reconstructive Surgery, Global Open
Background:. Plastic surgery in low- and middle-income countries (LMICs) has expanded during the past decades, but data reflecting trends and practices in plastic surgery in LMICs are scarce. This study reviewed trends and practice patterns in an LMIC to
Anup Thapa, MBBS, MS, Prajjwol Luitel, MBBS, Sujan Paudel, MBBS, Sadmarg Thakur, MBBS, Aron Shrestha, MBBS, Samit Sharma, MBBS, MS, MCh, Sangam Rayamajhi, MBBS, MS, MCh, Jayan Man Shrestha, MBBS, MS, FCPS, Ishwar Lohani, MBBS, MS, MCh   +8 more
doaj   +1 more source

“Yes! I Had Cosmetic Surgery”: Celebrities\u27 Comsmetic Surgery Confessions in the Media and Their Impact on Korean Female College Students\u27 Perceptions. [PDF]

, 2012
This paper analyzes celebrities’ cosmetic surgery confessions in the media and explores the impact of the confessions on non-celebrities. Based on the analysis of talk shows and online news in Korea today, I argue that celebrities’ confessions are the ...
Chae, Jiyoung
core   +1 more source

Results of Surgical Managment of Primary Mitral Regurgitation in a Single-center Study [PDF]

, 2017
Mitral regurgitation (MR) remains the second dominant defect in the structure of valvular cardiac diseases.It affects more than 2 million people in the USA.
Myshakivskyy, O. (Oleksiy)
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Circular belt lipectomy : a retrospective follow-up study on perioperative complications and cosmetic outcome [PDF]

, 2005
The purpose of this study was to evaluate the perioperative complications and cosmetic outcomes of circumferential belt lipectomy in patients with evident truncal excess.
Hofer, Stefan, Roche, Nathalie, van Huizum, Martine   +2 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Retrospective analysis of a personal casuistry in reduction mammoplasty using the inferior pedicle technique for various indications [PDF]

Revista Brasileira de Cirurgia Plástica, 2016
INTRODUCTION: Breast reduction surgery has been widely discussed, as different techniques are used to perform this procedure. The pursuit for aesthetics combined with surgical procedures that cause less unsightly scars promoted the development of ...
Leonardo Dalo de Oliveira
doaj   +1 more source

Multimodal Analgesia in the Aesthetic Plastic Surgery: Concepts and Strategies

Plastic and Reconstructive Surgery, Global Open, 2022
Background:. Postoperative pain management is crucial for aesthetic plastic surgery procedures. Poorly controlled postoperative pain results in negative physiologic effects and can affect length of stay and patient satisfaction.
Anna R. Schoenbrunner, MD, MAS, Girish P. Joshi, MBBS, MD, FFARCSI, Jeffrey E. Janis, MD   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source