Results 161 to 170 of about 70,909 (254)

A Single‐Cell Transcriptomic Atlas of the Ovine Rumen Microbiome Characterizes Lineage‐Specific Metabolic Shifts Associated with Host Heat Tolerance

open access: yesAdvanced Science, EarlyView.
An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang   +8 more
wiley   +1 more source

Biodegradation of plastic waste by yellow mealworms (<i>Tenebrio molitor</i> larvae). [PDF]

open access: yesPeerJ
Srisakvarangkool W   +5 more
europepmc   +1 more source

Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity

open access: yesAdvanced Science, EarlyView.
Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau   +22 more
wiley   +1 more source

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

open access: yesAdvanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen   +15 more
wiley   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

open access: yesAdvanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai   +9 more
wiley   +1 more source

Prevalence of plastic waste as a household fuel in low-income communities of the Global South. [PDF]

open access: yesNat Commun
Bharadwaj B   +40 more
europepmc   +1 more source

High‐Efficiency Precipitate Recycling Strategy Paves the Way for Efficient Sb2S3 Solar Cells Fabricated by CBD Method

open access: yesAdvanced Science, EarlyView.
A novel PR strategy was proposed to improve CBD‐derived Sb2S3 film quality. It synergistically optimized the CBO of CdS/Sb2S3 interface and the back‐contact barrier, while the VS2 donor defect was converted into SSb2 acceptor defect with lower concentration.
Yeyang Lin   +8 more
wiley   +1 more source

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