Results 121 to 130 of about 1,472,006 (329)

Role of MicroRNA in Governing Synaptic Plasticity [PDF]

, 2016
Yuqin Ye, Hongyu Xu, Xinhong Su, Xiaosheng He   +3 more
openalex   +1 more source

Central Adiponectin Signaling – A Metabolic Regulator in Support of Brain Plasticity

, 2022
Douglas Affonso Formolo, Tong Cheng, Jiasui Yu, Georg S. Kranz, Suk‐Yu Yau   +4 more
openalex   +2 more sources

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Coordinated activation of distinct Ca2+ sources and metabotropic glutamate receptors encodes Hebbian synaptic plasticity

Nature Communications, 2016
During STDP, the magnitude of postsynaptic Ca2+transients is hypothesized to determine the strength of synaptic plasticity. Here, the authors find that STDP in mature hippocampal synapses does not obey this rule but instead relies on the coordinated ...
Cezar M. Tigaret, Valeria Olivo, Josef H.L.P. Sadowski, Michael C. Ashby, Jack R. Mellor   +4 more
doaj   +1 more source

Glutamic Acid Decarboxylase 65: A Link Between GABAergic Synaptic Plasticity in the Lateral Amygdala and Conditioned Fear Generalization [PDF]

, 2014
Maren D. Lange, Kay Jüngling, Linda Paulukat, Marc Vieler, Stefano Gaburro, Ludmila Sosulina, Peter Blaesse, Hari Kishore Sreepathi, Francesco Ferraguti, Hans‐Christian Pape   +9 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Akkermansia muciniphila-induced trained immune phenotype increases bacterial intracellular survival and attenuates inflammation

Communications Biology
The initial exposure to pathogens and commensals confers innate immune cells the capacity to respond distinctively upon a second stimulus. This training capacity might play key functions in developing an adequate innate immune response to the continuous ...
Ainize Peña-Cearra, Ainhoa Palacios, Aize Pellon, Janire Castelo, Samuel Tanner Pasco, Iratxe Seoane, Diego Barriales, Jose Ezequiel Martin, Miguel Ángel Pascual-Itoiz, Monika Gonzalez-Lopez, Itziar Martín-Ruiz, Nuria Macías-Cámara, Naiara Gutiez, Sarai Araujo-Aris, Ana Mª Aransay, Héctor Rodríguez, Juan Anguita, Leticia Abecia   +17 more
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Upregulated energy metabolism in the Drosophila mushroom body is the trigger for long-term memory

Nature Communications, 2017
Energy consumption in the brain is thought to respond to changes in neuronal activity, without informational role. Here the authors show that increased energy flux in the mushroom body, driven by a pair of input dopaminergic neurons, is a command for the
Pierre-Yves Plaçais, Éloïse de Tredern, Lisa Scheunemann, Séverine Trannoy, Valérie Goguel, Kyung-An Han, Guillaume Isabel, Thomas Preat   +7 more
doaj   +1 more source

Extracellular matrix composition modulates PDAC parenchymal and stem cell plasticity and behavior through the secretome [PDF]

, 2018
Giulia Biondani, Katrine Zeeberg, Maria Raffaella Greco, Stefania Cannone, Ilaria Dando, Elisa Dalla Pozza, Maria Mastrodonato, Stefania Forciniti, Valeria Casavola, Marta Palmieri, Stephan J. Reshkin, Rosa Angela Cardone   +11 more
openalex   +1 more source