Results 181 to 190 of about 573 (225)

Observation and modeling of potential sub-threshold damage growth mechanism for nitinol in ultra-high cycle fatigue. [PDF]

Int J Fatigue
Roiko A, Cook S, Berg B, Falk W, Weaver JD.   +4 more
europepmc   +1 more source

PRMT9 Aggravated Dopaminergic Neurodegeneration in Parkinson's Disease Model by Facilitating the Degradation of DUSP26 and Inducing Mitochondrial Dysfunction

Advanced Science, EarlyView.
In the pathological state of PD induced by MPP+, the upregulated PRMT9 in dopaminergic neurons translocates into mitochondrion and interacts with DUSP26 and catalyzes its arginine methylation, leading to the ubiquitin‐proteasomal degradation of DUSP26 mediated by Trim32.
Tengfei Liu, Xiaomeng Song, Xin Guo, Rui Xiao, Ru Sun, Qiuran Ji, Lu Yu, Yiquan Li, Qingyi Fu, Qidi Xue, Lingjun Kong, Lin Chen, Chengjiang Gao, Huiqing Liu   +13 more
wiley   +1 more source

Large Language Model‐Informed Dual‐Track AI Framework for the Synergistic Design of Crack‐Free and High‐Strength Superalloys

Advanced Science, EarlyView.
This paper illustrates a knowledge‐augmented dual‐track AI framework for advanced superalloy design. First, Large Language Models translate metallurgical heuristics into explicit rules to rapidly prune a vast compositional search space. Subsequently, LLM‐distilled priors safely guide a reinforcement learning agent during autonomous process optimization,
Jian Yao, Junkang Wu, Jie Su, Fuzhu Wang, Zi Wang, Li Wang, Liming Tan, Lan Huang, Feng Liu, Yong Liu   +9 more
wiley   +1 more source

Cracking mechanism and acoustic emission characteristics of granite under varying thermal effects. [PDF]

Sci Rep
Cui Y, Xu C, Xue L, Bu F, Zhu J.
europepmc   +1 more source

Pemt Inhibition‐Mediated Vdac1 Oligomerization Regulates Mitochondrial Dysfunction, Apoptosis, and Inflammation in High‐Fat Diet‐Derived Liver Injury

Advanced Science, EarlyView.
ABSTRACT High‐fat diet (HFD)‐induced hepatic injury represents a pathology observed across vertebrates, yet the underlying mechanisms remain incompletely understood. Herein, the present study identifies phosphatidylethanolamine methyltransferase (Pemt), a key enzyme in phosphatidylcholine synthesis, as a critical regulator of mitochondrial homeostasis ...
Xianyong Bu, Xiufei Cao, Xin Yao, Baolin Li, Wencong Lai, Zengqi Zhao, Tingting Hao, Zhiwei Chen, Jianlong Du, Yueru Li, Kangsen Mai, Qinghui Ai   +11 more
wiley   +1 more source

Study on fold formation mechanism and process optimization in multi-directional die forged valve bodies. [PDF]

PLoS One
Niu L, Zhang Y, Zhang L, Zhang Q, Luo W, Wang J, Liu D, Ziaie B, Velay X.   +8 more
europepmc   +1 more source

Review on Main Controlling Factors and Key Simulation Techniques of Hydro-Fracturing Potential for Coalbed Methane Reservoirs: Recent Progress, Challenges, and Prospects. [PDF]

ACS Omega
Guo W, Wei Y, Cao D, Wang A, Jin L, Shi H, Lv H, Duan Z.   +7 more
europepmc   +1 more source

Elastic Energy Storage in Biological Materials: Internal Stresses and Their Functionality. [PDF]

Adv Mater
Amini S, Zaslansky P, Pokroy B, Fratzl P.   +3 more
europepmc   +1 more source

Simulation-Based Study on the Performance of NSM-CFRP Strengthening in Prestressed Concrete T-Beams Under Seismic Loading. [PDF]

Materials (Basel)
Haryanto Y, Hu HT, Atmajayanti AT, Hsiao FP, Nugroho L, Wariyatno NG.   +5 more
europepmc   +1 more source

Utilizing Excess Resin in Prepregs to Achieve Good Performance in Joining Hybrid Materials. [PDF]

Polymers (Basel)
Al-Ramahi NJ, Hassoni SM, Varna J, Joffe R.   +3 more
europepmc   +1 more source