Results 91 to 100 of about 48,781 (309)
IntroductionPreeclampsia (PE) and depressive disorder (DD) exhibit clinical comorbidity, yet the molecular mechanisms underlying this association remain poorly understood.MethodsDifferential expression analysis of placental and peripheral blood ...
Xinpeng Tian +7 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Experimental and Theoretical Study of Earth-Moist Concrete [PDF]
No ...
Brouwers, H.J.H., Hüsken, G.
core +1 more source
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
THE INFLUENCE OF RECIPE FORMULATION AND ELECTRIC FIELD FREQUENCY UPON DIELECTRIC LOSS IN PLASTIFIED PVC FILMS [PDF]
Plastified polyvinyl chloride (PVC) films are largely used in the clothing and footwear industries. The composition of the PVC-based blend and the curing stage determine the main characteristics of the final films.
BĂLĂU MÎNDRU Tudorel +2 more
doaj
New Natural Injection-Moldable Composite Material from Sunflower Oil Cake [PDF]
Through a twin-screw extrusion process the native structure of sunflower oil cake was completely transformed (globular protein denaturation/texturization and husk fiber defibration) into a simpler matrix-fiber structure, as could be seen on SEM ...
A. Rouilly +30 more
core +2 more sources
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Environmental pollutants are persistent chemicals that pose substantial risks to human health, contributing to global mortality and economic burden. In real-world situations, exposure rarely occurs to single compounds; instead, people are chronically ...
Francisco Alejandro Lagunas-Rangel
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source

