Results 21 to 30 of about 8,008 (166)

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

Advanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva, Sara Duarte‐Silva, Pedro M. Martins, Beatriz Rodrigues, Débora Serrenho, Daniela Vilasboas‐Campos, Andreia Teixeira‐Castro, Julio Vieyto‐Nuñez, Joel Mieres‐Perez, Francisco Figueiredo, Martyna Podlasiak, Tatiana Van‐der‐Kellen, Joana Fraga, James Noble, Carter Lantz, Niki Sepanj, Daniela Monteiro‐Fernandes, Sara Guerreiro, Andreia Neves‐Carvalho, Joana Pereira‐Sousa, Frank‐Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Annalisa Pastore, Elsa Sanchez‐Garcia, Gal Bitan, Ana Luísa Carvalho, Patrícia Maciel, Sandra Macedo‐Ribeiro   +28 more
wiley   +1 more source

Inteligencia Artificial Generativa integrada al ecosistema digital

InMediaciones de la Comunicación
Este artículo analiza el avance de la integración de las Inteligencias Artificiales Generativas a las plataformas, sobre todo la que se basan en los modelos de lenguaje grandes (LLMs).
Agustina Lassi
doaj   +1 more source

Afro‐Amerindian cosmopolitics in environmental education: A decolonial analysis of academic discourses involving the epistemological disputes around the term sustainability

British Educational Research Journal, EarlyView.
Abstract Considering the growing calls for decolonial approaches within the scope of Climate Change and Sustainability Education (CCSE), in this research we seek to understand the meanings which have been put into circulation through research narratives on Environmental Education (EE) concluded in Latin America, regarding Afro‐Amerindian knowledges ...
Danilo Seithi Kato, Luiz Marcelo de Carvalho   +1 more
wiley   +1 more source

Después de Internet

InMediaciones de la Comunicación
Traducción al español de la Introducción de After the Internet. Digital Networks between Capital and the Common, libro de Tiziana Terranova publicado por Semiotext(e) en 2022.
Tiziana Terranova
doaj   +1 more source

Las tecnologías de la información aplicadas a la educación Poscovid

Revista Metropolitana de Ciencias Aplicadas, 2023
Con el inicio del COVID, la humanidad debió adaptarse a un nuevo cambio en su forma de vida, de un momento a otro, las personas tuvieron que someterse a un encierro forzado, que ningún país pudo prever, y tampoco lo habían planificado.
Vladimir Sancho-Zurita, Ximena Crespo-Nuñez, Sylvia del Pilar Herrera-Díaz   +2 more
doaj   +1 more source

Adopting an Integrated Strategy in Local Policy Design: Agenda Content Diversity, Policy Capacities, and Policy Feedback Effects in Urban Policies as Multi‐Level Policy Mixes: The Urban Dimension of the European Union Cohesion Policy in Spain (1994–2020)

European Policy Analysis, EarlyView.
ABSTRACT Policy integration is seen as an appropriate strategy to address urban problems and promote sustainable urban development objectives. The European Union (EU) has been including this strategy as an essential aspect of its urban initiatives since the 1990s.
María José Dorado‐Rubín, Clemente J. Navarro, María José Guerrero‐Mayo   +2 more
wiley   +1 more source

La regulación del crowdfunding en Ecuador

USFQ Law Review, 2020
Hasta la última década, los mecanismos de financiamiento para el desarrollo de iniciativas con o sin fines de lucro, se han centralizado en el mercado financiero y mercado de valores.
Mario Alberto Cedeño Andrade
doaj   +1 more source

Experiences of disrespect and abuse during childbirth in the World Health Organization European region: A mixed‐method study among 22 countries

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Despite advancements in maternity quality care worldwide, mistreatment of women during childbirth persists. Currently, there is a gap of knowledge on the occurrence of disrespect and abuse during childbirth in the World Health Organization (WHO) European region.
Anna Galle, Helga Berghman, Ilaria Mariani, Maria Verdecchia, Arianna Bomben, Eline Skirnisdottir Vik, Daniela Drandic, Elizabete Pumpure, Raquel Costa, Helen Elden, Céline Miani, Barbara Baranowska, Antigoni Sarantaki, Zalka Drglin, Jelena Radetic, Alina Liepinaitienė, Virginie Rozée, Alessia Abderhalden‐Zellweger, Amira Cerimagic, Martina König‐Bachmann, Ourania Kolokotroni, Ilana Chertok, Maryse Arendt, Stefano delle Vedove, Ingvild Hersoug Nedberg, Magdalena Kurbanovic, Gunta Lazdane, Tiago Miguel Pinto, Karolina Linden, Stephanie Batram‐Zantvoort, Urszula Tataj‐Puzyna, Dimitra Metallinou, Anja Bohinec, Jovana Ružičić, Marija Mizgaitienė, Elise de La Rochebrochard, Michael Gemperle, Imola Simon, Maria Karanikola, Barbara Tasch, Simona Fumagalli, Marzia Lazzerini, on behalf of the IMagiNE EURO study group, Martina König‐Bachmann, Christoph Zenzmaier, Simon Imola, Elisabeth D’Costa, Anna Galle, Silke D’Hauwers, Amira Ćerimagić, Ourania Kolokotroni, Eleni Hadjigeorgiou, Maria Karanikola, Nicos Middleton, Ioli Orphanide Eteocleous, Daniela Drandić, Magdalena Kurbanović, Lenka Laubrova Zirovnicka, Miloslava Kramná, Rozée Virginie, Elise de La Rochebrochard, Kristina Löfgren, Céline Miani, Stephanie Batram‐Zantvoort, Antigoni Sarantaki, Dimitra Metallinou, Aikaterini Lykeridou, Ilana Chertok, Rada Artzi‐Medvedik, Marzia Lazzerini, Emanuelle Pessa Valente, Ilaria Mariani, Arianna Bomben, Stefano Delle Vedove, Sandra Morano, Antonella Nespoli, Simona Fumagalli, Elizabete Pumpure, Dace Rezeberga, Dārta Jakovicka, Gita Jansone‐Šantare, Anna Šibalova, Elīna Voitehoviča, Dārta Krēsliņa, Alina Liepinaitienė, želika Kondrakova, Marija Mizgaitienė, Simona Juciūtė, Maryse Arendt, Barbara Tasch, Enrico Lopriore, Thomas Van den Akker, Ingvild Hersoug Nedberg, Sigrun Kongslien, Eline Skirnisdottir Vik, Barbara Baranowska, Urszula Tataj‐Puzyna, Beata Szlendak, Paulina Pawlicka, Raquel Costa, Catarina Barata, Teresa Santos, Heloísa Dias, Tiago Miguel Pinto, Sofia Marques, Ana Meireles, Joana Oliveira, Mariana Pereira, Maria Arminda Nunes, Marina Ruxandra Otelea, Jelena Radetić, Jovana Ružičić, Zalka Drglin, Anja Bohinec, Serena Brigidi, Alejandra Oliden, Lara Martín Castañeda, Helen Elden, Karolina Linden, Mehreen Zaigham, Claire de Labrusse, Alessia Abderhalden‐Zellweger, Anouck Pfund, Harriet Thorn, Susanne Grylka, Michael Gemperle, Antonia Mueller   +126 more
wiley   +1 more source

Contenido

Gestión y Ambiente, 2010
Contenido
GYA GYA
doaj  

Sobrevivencia del derecho del trabajo frente a una potencial pérdida de su objeto producto de las nuevas formas de prestación de servicios

Revista de Derecho, 2019
Este trabajo tiene  por  finalidad  mostrar  los  desafíos  que  enfrenta  el Derecho  del  Trabajo  ante las nuevas formas de prestación de servicios a través de plataformas tecnológicas; dar cuenta de los riesgos de una visión pétrea respecto de la ...
Andres Eduardo Gidi Lueje
doaj   +1 more source