ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon +11 more
wiley +1 more source
An Lmx1a/b allelic series reveals the role of Lmx1 genes in cochlear nuclei development. [PDF]
Iskusnykh IY +4 more
europepmc +1 more source
A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source
Early clinical outcomes of standard and 3D-planned pre-bent hook plates versus suture-button fixation for acute Rockwood IIIB-V acromioclavicular dislocation with a Bigliani type II acromion: a retrospective cohort study. [PDF]
Lin J +11 more
europepmc +1 more source
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao +5 more
wiley +1 more source
Three-dimensional Interlocking versus conventional miniplates for mandibular fractures fixation near the mental foramen: a split-mouth randomized clinical trial. [PDF]
Abdelhamed IM +3 more
europepmc +1 more source
Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket +14 more
wiley +1 more source
Clinical outcomes and mechanical evaluation of patient-specific mandibular reconstruction following tumor resection: a retrospective study with finite element analysis. [PDF]
Do J, Han JJ, Lee JH, Kwon IJ.
europepmc +1 more source
Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr +5 more
wiley +1 more source
A Modified Warner and Fackler Technique With Posterior Plate for Kyphectomy in a Myelomeningocele Patient With Lumbar Kyphosis. [PDF]
Sarmiento JM +4 more
europepmc +1 more source

