Results 181 to 190 of about 76,641 (279)

Modeling the effects of treatment adherence challenges on the transmission dynamics of hepatitis C virus. [PDF]

open access: yesPLoS One
Mupedza TV   +6 more
europepmc   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux   +6 more
wiley   +1 more source

Analysis of C4 Concentrations to Predict Impact of Patient‐Reported Diarrhea Associated With the Ileal Bile Acid Transporter Inhibitor Linerixibat

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 596-605, March 2025.
ABSTRACT Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is being evaluated for the treatment of pruritus in primary biliary cholangitis (PBC). Diarrhea is commonly reported with this drug class as IBAT inhibition redirects bile acids (BA) to the colon.
Fernando Carreño   +4 more
wiley   +1 more source

An opportunity index to anticipate when subseasonal predictions are useful

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
Simultaneously active subseasonal windows of forecast opportunity can be combined into a single opportunity index, which can be used operationally to anticipate enhanced or reduced subseasonal prediction skill. For predictions of temperature anomalies in Switzerland during summer—a region and season with particularly low predictability—skill can nearly
Dominik Büeler   +4 more
wiley   +1 more source

Uncovering Exotic Topological Quantum States in Pure and Magnetically‐Doped Pyrite OsS2

open access: yesAdvanced Quantum Technologies, EarlyView.
Pyrite‐structured OsS2 is identified as a fragile topological insulator with an unprecedented 602 meV bandgap, featuring helical surface states and van Hove singularities amenable to ARPES verification. Magnetic doping with Pd, Fe, Ni, or Co induces phase transitions to strong topological insulators, semimetals, 3D quantum anomalous Hall insulators ...
Ali Sufyan   +9 more
wiley   +1 more source

Loss Behavior in Supervised Learning With Entangled States

open access: yesAdvanced Quantum Technologies, EarlyView.
Entanglement in training samples supports quantum supervised learning algorithm in obtaining solutions of low generalization error. Using analytical as well as numerical methods, this work shows that the positive effect of entanglement on model after training has negative consequences for the trainability of the model itself, while showing the ...
Alexander Mandl   +4 more
wiley   +1 more source

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