Results 71 to 80 of about 25,010 (268)

Advancing the Identification of Bioactive Molecules and the Construction of a Synergistic Drug Delivery System in Combating Lung Injury

Advanced Science, EarlyView.
Traditional Chinese Medicine (TCM), while holistic and historically esteemed, faces challenges in “miracle cures” due to slow onset, long cycles, and difficulty controlling quality. This study obtains the active ingredients, glabridin (GLA) and puerarin (PUE), from Ge‐Gen Decoction (GGD), developing a safe and effective drug delivery system, GLA‐PUE ...
Jianhong Qi, Yanxia Wang, Huan Chen, Kaitian Wu, Pei Zhou, Yue Dou, Bingqi Xiong, Wei Zhou   +7 more
wiley   +1 more source

A historical review of experimental imaging of the beating heart coronary microcirculation in vivo

Journal of Anatomy, Volume 242, Issue 1, Page 3-16, January 2023., 2023
Intravital imaging of the beating heart microcirculation in vivo has been challenging. The past 50 years has seen changes in ways to both stabilise and image the heart with a shift from learning about coronary vascular anatomy and physiology to the role of thromboinflammation and other microcirculatory disturbances in cardiovascular disease.
Neena Kalia
wiley   +1 more source

Influence of Injectable Platelet-Rich Fibrin on ex vivo Leak Pressure of Canine Enterotomy [PDF]

Iranian Journal of Veterinary Surgery
Injectable platelet rich fibrin, the latest innovation among platelet concentrates is obtained by centrifugation of whole blood without any anticoagulants. The initially liquid product is later converted into gel form due to conversion of fibrinogen into
Ali Heydari Azar Heris, Davoud Kazemi
doaj   +1 more source

Applications of platelet rich fibrin in dentistry

Gülhane Tıp Dergisi, 2022
Platelet-rich fibrin (PRF), a second-generation platelet concentrate, comprises a fibrin matrix containing numerous growth factors. These growth factors are involved with the cells responsible for the processes of tissue repair, regeneration, and growth.
Mamatha Shetty, Srikala Bhandary
doaj   +1 more source

Catheter Injectable Multifunctional Biomaterial for the Treatment of Infected Enterocutaneous Fistulas

Advanced Science, EarlyView.
A multi‐functional shear‐thinning hydrogel is engineered to treat enterocutaneous fistulas. This hydrogel can resist external pressures allowing it to remain within the fistula tract and is shown to have significant antimicrobial, pro‐healing, and anti‐inflammatory properties, which were validated in in vitro and in vivo experiments.
Jinjoo Kim, Zefu Zhang, Hassan Albadawi, Hyeongseop Keum, Joseph L. Mayer, Erin H. Graf, Rahmi Oklu   +6 more
wiley   +1 more source

Advancements in left ventricular assist devices to prevent pump thrombosis and blood coagulopathy

Journal of Anatomy, Volume 242, Issue 1, Page 29-49, January 2023., 2023
Left ventricular assist device (LVAD)‐related blood coagulopathy: Pump thrombosis is one of the most severe adverse events caused by LVADs. The contact of blood with artificial materials of LVAD pumps and cannulas triggers the coagulation cascade. Abstract Mechanical circulatory support (MCS) devices, such as left ventricular assist devices (LVADs) are
Grainne Malone, Gerges Abdelsayed, Fianait Bligh, Fatma Al Qattan, Saifullah Syed, Prateepan Varatharajullu, Augustin Msellati, Daniela Mwipatayi, Maimoona Azhar, Andrew Malone, Saulat H. Fatimi, Claire Conway, Aamir Hameed   +12 more
wiley   +1 more source

Role of Platelet Concentrates in Dental-Pulp Regeneration: A Systematic Review of Randomized Clinical Trials [PDF]

Journal of Dentistry
Statement of the Problem: Treatment of immature necrotic teeth is a problematic situation. Conventional root canal therapy is challenging and leaves a weak, fragile and undeveloped tooth for lifetime.Purpose: This review was aimed to assess the outcome ...
Zahra Kiaipour, Mahdieh Shafiee, Ghasseem Ansari   +2 more
doaj   +1 more source

Tumor Microenvironment Triggered In Situ Coagulation of Supramolecularly Engineered Platelets for Precise Tumor Embolization

Advanced Science, EarlyView.
Occlusion of tumor blood vessels represents a promising yet challenging approach in cancer treatment. Herein, supramolecularly engineered platelets conjugated with morphology‐transformable nanoparticles is developed for precise tumor embolization. The engineered platelets actively accumulate at tumor sites following induced blood vessel injury.
Junyan Li, Ziyi Wang, Ruifeng Luo, Xingping Quan, Hong U Fong, Qian Cheng, Jianwen Wei, Leo Wang, Yonghua Zhao, Ruibing Wang   +9 more
wiley   +1 more source

Developing an unfolding-incorporated coarse-grained polymer model for fibrinogen to study the mechanical behaviour [PDF]

Northeast Journal of Complex Systems (NEJCS): Vol. 7 : No. 1 , Article 10 (2025); Special Issue: IC2SMA2 2025 Conference proceedings
Fibrinogen is a protein found in blood that forms Fibrin polymer network to build a clot during wound healing process when there is a cut in the blood vessel. The fibrin fiber is highly stretchable and shows a complex mechanical properties. The fibrin monomer, Fibrinogen, has a very complex structure which is responsible for its unusual elastic ...
arxiv   +1 more source

Porosity governs normals stresses in polymer gels [PDF]

Phys. Rev. Lett. 117, 217802 (2016), 2016
When sheared, most elastic solids such as metals, rubbers and polymer hydrogels dilate in the direction perpendicular to the shear plane. This well-known behaviour known as the Poynting effect is characterized by a positive normal stress. Surprisingly, biopolymer gels made of fibrous proteins such as fibrin and collagen, as well as many biological ...
arxiv   +1 more source