Exogenous application of platelet-leukocyte gel during open subacromial decompression contributes to improved patient outcome [PDF]
Background: Platelet-leukocyte gel (PLG) is being used during various surgical procedures in an attempt to enhance the healing process. We studied the effects of PLG on postoperative recovery of patients undergoing open subacromial decompression (OSD ...
Devilee, R. +7 more
core +2 more sources
The aim of the present study was to evaluate the effect of injectable platelet-rich fibrin (i-PRF) on cultivated chondrocytes and osteochondral regeneration in critical-sized osteochondral defect of the rabbit’s knee in comparison to autologous platelet ...
Mustafa Abd El Raouf +10 more
semanticscholar +1 more source
Warwick hip trauma study : a randomised clinical trial comparing interventions to improve outcomes in internally fixed intracapsular fractures of the proximal femur : protocol for The WHiT Study [PDF]
Background Controversy exists regarding the optimal treatment for patients with displaced intracapsular fractures of the proximal femur. The recognised treatment alternatives are arthroplasty and internal fixation.
Achten, Juul +3 more
core +5 more sources
Platelet-rich plasma in osteoarthritis treatment: review of current evidence
Platelet-rich plasma (PRP) is defined as a volume of plasma with a platelet concentration higher than the average in peripheral blood. Many basic, preclinical and even clinical case studies and trials report PRP’s ability to improve musculoskeletal ...
L. Gato-Calvo +4 more
semanticscholar +1 more source
Orthobiologics and platelet rich plasma
Orthobiologics have evolved to the extent that they significantly influence modern orthopedic surgical practice. A better understanding of the role of various growth factors and cells in the process of tendon healing, ligament repair, cartilage regeneration and bone formation has stimulated focused research in many chronic musculoskeletal ailments ...
Dhillon, Mandeep S +3 more
openaire +3 more sources
Smoking-induced long-lasting modifications of human platelet serotonin catabolism through a MAO epigenetic regulation [PDF]
Postulating that serotonin, secreted from smoking-activated platelets, could be involved in smoking-induced vascular modifications, we studied 115 men distributed in smokers (S), former smokers (FS) and never smokers (NS).
Alain Simon +8 more
core +1 more source
As a minimally invasive treatment option, intra-articular injection of platelet-rich plasma (PRP) has been widely used in clinical therapy. Our meta-analysis showed that PRP injections constitute an effective and safe alternative treatment for long-term ...
Yanhong Han +7 more
semanticscholar +1 more source
Platelet rich plasma is an autologous concentration of eight growth factors PDGF -AA, PDGF -BB ,PDGF -AB,Transforming growth factor β 1 and β2 ,vascular endothelial growth factor (VEGF) ,epidermal growth factor (EGF) ,and insulin like growth factor . Nowadays PRP is widely used in all the fields of dentistry .This article explains the various potential
openaire +2 more sources
Repurposing cancer drugs, batimastat and marimastat, to inhibit the activity of a group I metalloprotease from the venom of the Western Diamondback rattlesnake, Crotalus atrox [PDF]
Snakebite envenomation causes over 140,000 deaths every year predominantly in developing countries. As a result, it is one of the most lethal neglected tropical diseases.
Bicknell, Andrew B. +12 more
core +1 more source
Platelet-rich plasma-derived extracellular vesicles improve liver cirrhosis in mice
Introduction: Cirrhosis remains a significant clinical challenge due to its poor prognosis and limited treatment options, creating a high unmet medical need for the development of novel therapies.
Yuichirou Maeda +11 more
doaj +1 more source

