Results 181 to 190 of about 140,688 (406)

39. HIGH PREOPERATIVE PLATELET TO LYMPHOCYTE RATIO IS ASSOCIATED WITH A GREATER RISK OF POSTOPERATIVE COMPLICATIONS AND RECURRENCES IN ESOPHAGEAL CANCER [PDF]

open access: bronze, 2023
Masahiro Sasahara   +10 more
openalex   +1 more source

Prognostic Utility of the Preoperative Cachexia Index in Patients Undergoing Emergency Laparotomy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
The preoperative cachexia index, incorporating muscle mass, nutritional status, and inflammation, predicts in‐hospital and one‐year mortality in patients undergoing emergency laparotomy. This simple index may aid in risk stratification and perioperative decision‐making in high‐risk surgical patients. ABSTRACT Aim Emergency laparotomy is associated with
Naoko Fukushima   +6 more
wiley   +1 more source

To Evaluate Whether Pretreatment CA19‐9 and DUPAN‐2 Levels Can Serve as Predictive Markers to Guide the Choice Between NAT and Upfront Surgery in Pancreatic Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
NAT‐GS was significantly more effective only in patients with one tumor marker above the reference range, comparing those who achieved 12‐month MRFS with those who did not. ABSTRACT Aim Pancreatic cancer (PC) remains one of the most lethal malignancies, with early recurrence severely affecting prognosis even after curative resection.
Hiromichi Kawaida   +9 more
wiley   +1 more source

Prognostic biomarkers in COVID-19 infection: value of anemia, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and D-dimer [PDF]

open access: diamond, 2021
Maiada K. Hashem   +10 more
openalex   +1 more source

The National Clinical Database Risk Calculator and the 5‐Item Modified Frailty Index Predict the Development of Postoperative Delirium After Surgery for Hepatocellular Carcinoma

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This study demonstrates that combining the NCD Risk Calculator with the mFI‐5 enables more precise stratification of postoperative delirium risk in patients undergoing surgery for HCC. Patients classified as high risk by the combined model showed a markedly higher incidence of delirium than those in the intermediate‐ and low‐risk groups.
Kiyotaka Hosoda   +9 more
wiley   +1 more source

Effect of Red Blood Cell Transfusion on Inflammatory and Angiogenic Pathways in Patients With Sickle Cell Disease

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Sickle cell disease (SCD) is a chronic inflammatory state, characterized by increased plasma values of inflammatory and angiogenic proteins. Although red blood cell (RBC) transfusion is known to have immunomodulatory effects in other conditions, its potential effects on the inflammatory state in SCD remain largely unknown.
Lydian A. de Ligt   +9 more
wiley   +1 more source

A Murine Bispecific Antibody Efficiently Redirects T Cells Against Calr Mutated Stem Cells In Vivo

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Calreticulin (CALR) mutations are prevalent in 20%–30% of patients with BCR::ABL1‐negative myeloproliferative neoplasms (MPN). Mutant calreticulin (mutCALR), presented by the thrombopoietin receptor (MPL, also known as TPOR or CD110) on the surface of the disease‐initiating MPN progenitors, represents an ideal target for curative ...
Shengen Xiong   +5 more
wiley   +1 more source

Development of an in situ small intestinal injection technique for targeted macromolecule delivery and in vivo functional studies in mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study developed a minimally invasive, in situ small intestinal injection technique for mice, enabling targeted delivery of bioactive molecules while bypassing gastric degradation. Validation using functional assays and single‐cell RNA sequencing reveals high‐mobility group box 1–mediated epithelial responses, offering a translational tool for gut ...
Yawen Lai   +7 more
wiley   +1 more source

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