Results 351 to 360 of about 140,688 (406)

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

Association Between Platelet-to-Lymphocyte Ratio and Insulin Resistance in Cancer Survivors: A Cross-Sectional Study Based on the NHANES 2005 - 2018. [PDF]

World J Oncol
Wang J, Li T.
europepmc   +1 more source

Effective dose to immune cells combined with platelet-to-lymphocyte ratio predicts lymphopenia and prognosis in unresectable locally advanced non-small cell lung cancer. [PDF]

Front Immunol
Yang H, Ma J, Tian C, Bao S, Zhang J, Wang F, Xu Y, Yu J, Chen D.   +8 more
europepmc   +1 more source

A Nomogram Combining Platelet to Lymphocyte Ratio (PLR) and Systemic Inflammatory Response Index (SIRI) to Predict Patients with <i>H. pylori</i> -Positive Gastric Dysplasia. [PDF]

J Multidiscip Healthc
Fang JW, She Q, Xia JL, Chen YY, Liu ZQ, Yu Y, Fu XY, Jiang X, Li YY, Zhang M, Ding YB.   +10 more
europepmc   +1 more source

The diagnostic significance of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in malaria: insights and implications - a narrative review. [PDF]

Ann Med Surg (Lond)
Obeagu EI.
europepmc   +1 more source

Inflammatory markers in primary and secondary premature ejaculation: clinical significance of the neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios

Üntan, İbrahim
openalex   +1 more source

Posttraumatic plasma levels of mediators of organ failure [PDF]

, 1988
Dwenger, A., Jochum, Marianne, Joka, T., Redl, H., Schlag, G., Sturm, J.   +5 more
core  

Prognostic value of platelet to lymphocyte ratio (PLR) in breast cancer patients receiving neoadjuvant therapy: a systematic review and meta-analysis. [PDF]

Front Immunol
Zhao Z, Xu H, Ma B, Dong C.
europepmc   +1 more source

Platelet-to-lymphocyte ratio as a prognostic biomarker in patients with human epidermal growth factor receptor 2-negative breast cancer undergoing taxane-carboplatin-based neoadjuvant chemotherapy. [PDF]

Ther Adv Med Oncol
Huang Q, Huang K, Qian J, Yang Y.
europepmc   +1 more source