Results 71 to 80 of about 88,871,866 (251)

Multiple Loci Are Associated with White Blood Cell Phenotypes [PDF]

open access: yes, 2011
White blood cell (WBC) count is a common clinical measure from complete blood count assays, and it varies widely among healthy individuals. Total WBC count and its constituent subtypes have been shown to be moderately heritable, with the heritability ...
Taylor, K   +606 more
core   +1 more source

Mean Platelet Volume and the Ratio of Mean Platelet Volume/Platelet Count in Acute Rheumatic Fever

open access: yes, 2021
Aim:Acute rheumatic fever (ARF) is an endemic disease especially in developing countries. Due to an autoimmune response to group B streptococcus throat infection, ARF develops in susceptible children. Mean platelet volume (MPV) reflects the platelet size
Gürses, D.   +5 more
core   +1 more source

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello   +10 more
wiley   +1 more source

Can Hematological Parameters Indicate Possible Inflammatory Mechanisms in Children with Intellectual Disability?

open access: yesErciyes Medical Journal, 2020
Objective: This study aims to interpret the hematological parameters of children with the intellectual disability and to show the relationship between hematological parameters and possible inflammatory mechanisms of intellectual disability. Materials and
Pembe Soylu Üstkoyuncu   +4 more
doaj   +1 more source

Platelet and white blood-cell-based ratios: Differential inflammatory markers of severe mental disorders?

open access: yesSpanish Journal of Psychiatry and Mental Health
Neutrophil/lymphocyte (NLR), monocyte/lymphocyte (MLR), and platelet/lymphocyte (PLR) ratios, and systemic inflammatory index (SII) represent peripheral markers of inflammation associated with different severe mental disorders.In this study, these parameters were analyzed in a sample of 622 participants [197 patients with major depressive disorder (MDD)
Paniagua, Gonzalo   +9 more
openaire   +3 more sources

Genetic studies of hereditary thrombocythemia [PDF]

open access: yes, 2013
Hereditary thrombocythemia (HT) is a familial myeloproliferative disorder characterized by an elevated platelet count in peripheral blood. Thrombocytosis is due to a genetic alteration that can be transmitted to the offspring.
Pianta, Annalisa
core   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns   +2 more
wiley   +1 more source

Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein [PDF]

open access: yes, 2006
Oxidation of low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that play a crucial role in cardiovascular and inflammatory diseases.
Wolfgang Siess, Siess, Wolfgang
core   +1 more source

Alterations in Platelet-to-Lymphocyte Ratio, and Some White Blood Cell Indices in Neonatal Thrombocytopenia

open access: yesSokoto Journal of Medical Laboratory Science, 2020
Platelets, Neutrophils, Lymphocytes, Neutrophil-to-Lymphocyte ratio (NLR) and Platelet‑to‑Lymphocyte ratio (PLR) have been studied as haematological and biologic markers of infections and inflammation; however, changes in PLT, NLR and some white blood ...
Collins Ohwonigho Adjekuko * , Etim Emmanuel Asuquo , Mathias Abiodun Emokpae, Humphrey Benedo Osadolor and Zaccheaus Awortu Jeremiah
doaj  

Anti-platelet therapy: ADP receptor antagonists. [PDF]

open access: yes, 2011
The P2Y(12) receptor on platelets with which ADP interacts has an important role in promoting platelet function and thereby platelet involvement in both haemostasis and thrombosis.
Heptinstall, S   +3 more
core   +1 more source

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