Results 351 to 360 of about 1,682,982 (408)
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Platelet calmodulin correlates with platelet turnover
European Journal of Haematology, 1990Abstract: We measured the calmodulin content in platelets in 13 normal persons and in 62 patients with hematological diseases. The level of platelet calmodulin was higher in patients with idiopathic thrombocytopenic purpura (ITP), systemic lupus erythematosus, myeloproliferative disorders, acute leukemia in a recovery phase, aplastic anemia ...
N, Endoh +4 more
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Platelet Formation, Platelet Density and Platelet Ageing
1990Microscopic examination of both platelets and megakaryocytes shows them to vary widely in size and ultrastructure. This structural diversity was noted by early investigators (Bunting 1909) and interest in its origin and significance has continued to the present day.
K. G. Chamberlain +2 more
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Status of Platelet Collection and Platelet Transfusion
Therapeutic Apheresis, 2001Abstract: Platelet product derived from single donor plateletpheresis is required to reduce the risks of adverse reactions by blood transfusion. The objectives of this study are to evaluate the status of platelet collection and its efficacy by various kinds of plateletpheresis equipment and to assess the achievement of platelet transfusion by platelet ...
S, Omokawa +9 more
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Platelet substitutes and novel platelet products
Expert Opinion on Investigational Drugs, 2000Despite many advances in the safety, processing and storage of conventional 22 degrees C liquid-stored allogeneic platelet concentrates, there are still significant drawbacks to standard platelet concentrates used in transfusions for patients with thrombocytopenia.
D H, Lee, M A, Blajchman
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Platelet Aggregometry and Anti-Platelet Isoantibodies
Pathophysiology of Haemostasis and Thrombosis, 1975102 sera from polytransfused patients have been screened in platelet aggregometry. Anti-human platelet isoantibodies, tested against ‘responsive’ human platelets in PRP, give in the aggregometer a decrease in optical density recorded as a sigmoidal curve.
E, Pogliani +5 more
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Mechanism and control of platelet-platelet interactions
Microvascular Research, 1972Abstract With the technique of shadow-casting of whole platelets, it has been possible to observe both the very early events produced on the platelet surface by aggregating agents and what appears to be the entire process of platelet aggregation. It has been shown that a variety of aggregating agents and conditions such as ADP, thrombin, collagen ...
François M. Booyse +3 more
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Platelet aggregation and platelet-inhibiting drugs
Neurochemical Pathology, 1987Platelet function may cause a progression of central gray matter damage after cerebrospinal hemorrhage or trauma because of the thrombotic occlusion of injured vessels or a vasospasm induced by extravasated blood. It has therefore been suggested that antiplatelet drugs could limit the extent of the neurological lesions produced by a spinal trauma.
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Platelet Count and Platelet Stickiness in Rats
Thrombosis and Haemostasis, 1971SummaryIn rat, a transected tail vessel proved an adequate source of blood for platelet enumeration. When suspensions of rat blood in ammonium oxalate were rotated for 1 h a significant loss of platelets was observed. This platelet reduction rate (PRR), calculated as per cent of the pre-rotation count, showed individual constancy and inter-individual ...
O P, Grüner, G K, Endresen
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Platelet Activity in Washed Platelet Concentrates
Anesthesia & Analgesia, 2004Life-threatening anaphylaxis or febrile nonhemolytic transfusion reactions after transfusion of platelet concentrates (PCs) is a serious clinical problem caused by the sensitizing of recipients to plasma components, such as immunoglobulin A, or by cytokines. There is a possible indication for washing of PCs in these thrombocytopenic patients.
Helge, Schoenfeld +4 more
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Platelet Glycolysis in Platelet Storage
Transfusion, 1979The metabolism of exogenous citrate by freshly collected human platelets has been investigated by measuring the disappearance of citrate from platelet suspensions and by measuring the formation of C02 and glycogen from purified radioactive citrate. These studies indicate that platelets do not have the capacity to metabolize exogenous citrate.
C, Tegos, E, Beutler
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