Results 311 to 320 of about 1,044,846 (392)
A novel form of integrin dysfunction involving beta 1, beta 2, and beta 3 integrins [PDF]
Hogg, N+6 more
core
The formation pathways of CuInS2 quantum dots are explored through in situ and ex situ characterization. The Lewis acid strength of cation precursors dictates synthesis routes, leading to either indirect or direct nucleation. These routes significantly impact the electrical and photoelectrochemical properties.
Hyo Cheol Lee+17 more
wiley +1 more source
A novel biodegradable wound dressing (E‐PCLs) based on polycaprolactone (PCL) and an enzyme complex (RHP‐BCL) is developed using a fiber microfluidic electrospinning technique. The dressing achieves complete degradation within 14 days, eliminates microplastic residues, and promotes scar‐free healing (99% in 21 days).
Lingling Fan+7 more
wiley +1 more source
Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection
The elevated expression of Capn2 in endothelial cells activates focal adhesion signaling by cleaving Talin1 and assembling Itgav, which compromises the integrity of the endothelial barrier and induces vascular inflammation. Inhibition of calpain through both pharmacological and transgenic approaches has effectively suppressed the onset and progression ...
Xiaomei Teng+10 more
wiley +1 more source
Platelet-activating factor: a phospholipid autacoid with diverse actions
ME Venable+3 more
doaj
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The role of platelet-activating factor in platelet aggregation
Nature, 1979PLATELET aggregation is mediated by at least three distinct mechanisms1,2. The first involves the release of ADP and is inhibited by its conversion to ATP by the combination of creatine phosphate and creatine phosphokinase (CP/CPK). The second is mediated by metabolites of arachidonic acid, particularly thromboxane A2 (TXA2), and is blocked by aspirin ...
J P Le Couedic+4 more
openaire +4 more sources
Platelet Activating Factor (PAF): A Mediator of Inflammation
Biofactors, 2022Platelet‐activating factor (PAF) is a phospholipid‐derived mediator with an established role in multiple inflammatory states. PAF is synthesized and secreted by multiple cell types and is then rapidly hydrolyzed and degraded to an inactive metabolite ...
J. Upton+3 more
semanticscholar +1 more source
COVID‐19, microthromboses, inflammation, and platelet activating factor
Biofactors, 2020Recent articles report elevated markers of coagulation, endothelial injury, and microthromboses in lungs from deceased COVID‐19 patients. However, there has been no discussion of what may induce intravascular coagulation.
C. Demopoulos+2 more
semanticscholar +1 more source
Platelet-activating factor receptor
Prostaglandins & Other Lipid Mediators, 2002Platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is a biologically active phospholipid mediator. Although PAF was named for its potential to induce platelet aggregation, intense investigations have elucidated potent biological actions of PAF in a broad range of cell types and tissues.
Takahide Nagase+2 more
openaire +5 more sources