Results 331 to 340 of about 1,055,543 (397)
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Platelet-activating factor and asthma
Journal of Allergy and Clinical Immunology, 1988anaphylaxis. And if you research into the 1920s) there a very useful treatment in blocking both thrombocyare articles, particularly in the German literature, that topenia and some of the features of anaphylaxis. The report thrombocytopenia as being a feature of clinical first article (1924) stated that heparin totally prevents asthma.
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Platelet-activating factor antagonists
Clinical Reviews in Allergy, 1995The great number of PAF antagonists reviewed in this article clearly shows the tremendous effort made in the last 20 yr to explore the complex biological background of the mechanism of action of PAF and the potential clinical benefit of its antagonists. It is obvious that now highly potent, long-acting, and perorally applicable PAF-receptor antagonists
Pierre Braquet, Matyas Koltai
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PLATELET-ACTIVATING FACTOR IN THE CNS
Progress in Neurobiology, 1996Platelet-activating factor (PAF) is a phospholipid synthesized in a variety of cells throughout the body. Platelet-activating factor has been identified in the CNS and has a number of diverse physiological and pathological functions. It has been shown to be a modulator of many CNS processes, ranging from long-term potentiation (LTP) to neuronal ...
Karyn Maclennan +2 more
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Platelet-activating factor and the kidney
American Journal of Physiology-Renal Physiology, 1986Platelet-activating factor (PAF) represents a group of phospholipids with the basic structure of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine. A number of different cells are capable of producing PAF in response to various stimuli. The initial step of PAF formation is activation of phospholipase A2 in a calcium-dependent manner, yielding lyso-PAF ...
R. Neuwirth, D. Schlondorff
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Platelet Factor 3 Activity in Washed Platelets [PDF]
Thrombosis and Haemostasis, 1973 SummaryPlatelets collected with an EDTA solution and simply washed in an incomplete Tyrode’s presented clotting times in the recalcification (man and rat) and the Stypven (rat) tests that were practically identical to those of the PRP when slow speed centrifugation was used (800 G in man, 1000 G in rat). This was demonstrated, in 6 pools of 5 rats each
S Renaud, P. Gautheron, H Rosenstein
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Platelet-Activating Factor and Platelet-Activating Factor Antagonists in Acute Pancreatitis
Digestive Surgery, 1999<i>Introduction:</i> Acute pancreatitis causes platelet-activating factor (PAF) to be released which induces systemic effects that contribute to circulatory disturbances and multiple organ failure. PAF has also been implicated as a key mediator in the progression of severe acute pancreatitis, which can lead to complications and unacceptably
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2000
Research leading to the discovery of platelet-activating factor (PAF) came from studying a reaction that triggered platelets to release histamine. It was attributed to a factor actively released from leukocytes. Platelet-activating factor was first identified by Benveniste et al. in 1972.1 Later it was recognized that this phospholipid mediator is also
W. A. Buurman +3 more
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Research leading to the discovery of platelet-activating factor (PAF) came from studying a reaction that triggered platelets to release histamine. It was attributed to a factor actively released from leukocytes. Platelet-activating factor was first identified by Benveniste et al. in 1972.1 Later it was recognized that this phospholipid mediator is also
W. A. Buurman +3 more
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Platelet Activating Factor and Conception
American Journal of Reproductive Immunology, 1996PURPOSE: This review provides evidence for the involvement of platelet activating factor (PAF) in the several facets of pregnancy establishment.METHODS: A comprehensive literature review and new data.RESULTS: PAF has a role in spermatozoal function, fertilization, embryo development, and implantation.CONCLUSIONS: PAF is intimately involved in ...
N. Gleicher +5 more
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Revue Française d'Allergologie et d'Immunologie Clinique, 1977
Resume Il existe dans les basophiles et les mastocytes de nombreuses especes de mammiferes un facteur agregeant les plaquettes qui represente par consequent un lien entre la pathologie liee a la degranulation des basophiles/mastocytes, c'est-a-dire l'hypersensibilite immediate, et les plaquettes sanguines.
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Resume Il existe dans les basophiles et les mastocytes de nombreuses especes de mammiferes un facteur agregeant les plaquettes qui represente par consequent un lien entre la pathologie liee a la degranulation des basophiles/mastocytes, c'est-a-dire l'hypersensibilite immediate, et les plaquettes sanguines.
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Platelet-Activating Factor Antagonists
Annual Review of Pharmacology and Toxicology, 1987Over the past decade platelet-activating factor has achieved the status of an important inflammatory mediator. The scientific enthusiasm and number of research investigators, publications, and meetings recently devoted to PAF suggest that this mediator will be the subject of continued study in the foreseeable future.
R N Saunders, D A Handley
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