Results 331 to 340 of about 4,080,787 (408)

Preferential and sustained platelet activation in COVID-19 survivors with mental disorders. [PDF]

Sci Rep
Maugeri N, De Lorenzo R, Mazza MG, Palladini M, Ciceri F, Rovere-Querini P, Manfredi AA, Benedetti F.   +7 more
europepmc   +1 more source

Irisin Attenuates Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension via Ubiquitin‐Mediated Regulation of ENO1

Advanced Science, EarlyView.
Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun, Yong‐Bing Wang, Jing Huang, Run‐Wei Deng, Hui‐Yu He, Lei Gao, Xuan Gao, You‐Li Fan, Yan Cong, Yao‐Lei Guo, Yi‐Qiang Chen, Gui‐Jia Wang, Shao‐Hong Fang, Xia Gu, Bo Yu, Bing‐Xiang Wu   +15 more
wiley   +1 more source

High‑fat diet‑induced LCN2 exacerbates myocardial ischemia‑reperfusion injury by enhancing platelet activation. [PDF]

Mol Med Rep
Li P, Chen J, Wang M, Wang Q, Liu X.
europepmc   +1 more source

Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines

Advanced Science, EarlyView.
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li, Ya‐Li Zhang, Tong Jin, Zhaokui Jin, Mengliang Zhu, Guangchao Qing, Jinchao Zhang, Zhisen Wang, Yan Mu, Jin Li, Qian Hua, Xing‐Jie Liang   +11 more
wiley   +1 more source

Curcumin Modulates Platelet Activation and ROS Production Induced by Amyloid Peptides: New Perspectives in Attenuating Prothrombotic Risk in Alzheimer's Disease Patients. [PDF]

Nutrients
Rustichelli S, Lanni C, Zarà M, Guidetti GF, Torti M, Canobbio I.   +5 more
europepmc   +1 more source

PTf‐SRiApt Targeting SCAF4‐POLR2A Interaction Suppresses Tumor Growth and Promotes Antitumor Immunity in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A phosphorothioate‐modified aptamer PTf‐SRiApt capable of disrupting “undruggable” transcription factor SCAF4‐POLR2A interaction with high inhibitory activity and biological stability is presented here. Through this inhibition, PTf‐SRiApt successfully arrested cell cycle progression, induced cell death, and elevated immune recruitment in SCAF4‐POLR2A ...
Liyan Fei, Yichun Pan, Jie Zhai, Tongqing Li, Yuxin Zhou, Sheyu Zhang, Juan Wei, Qian Hu, Xueying Liu, Lu Guo, Weizhu Wu, Yong Wei, Qin Wu, Weihong Tan   +13 more
wiley   +1 more source

Editorial expression of concern: Lipoxin A4 analogue, BML-111, reduces platelet activation and protects from thrombosis. [PDF]

Thromb J
AlOmar S, Mitchell JL, AlZahrani E.
europepmc   +1 more source

Hemin-induced platelet activation is regulated by the ACKR3 chemokine surface receptor and has implications for passivation of vulnerable atherosclerotic plaques. [PDF]

FEBS J
Laspa Z, Dicenta-Baunach V, Schaale D, Sigle M, Hochuli R, Castor T, Bayrak A, Harm T, Müller KAL, Pillaiyar T, Laufer S, Rohlfing AK, Gawaz MP.   +12 more
europepmc   +1 more source

Relevance of anti-platelet factor 4/heparin antibodies and platelet activation in systemic inflammatory diseases and thrombosis disorders: insight from the COVID-19 pandemic. [PDF]

Res Pract Thromb Haemost
Gendron N, Helley D, Thaler J, Faille D, Le Beller C, Gruest M, Hadjadj J, Philippe A, Zeco F, Courbebaisse M, Darnige L, Amara W, Calmette L, Parfait B, Auditeau C, Chocron R, Khider L, Mauge L, Espitia O, Friedlander G, Ajzenberg N, Lebeaux D, Planquette B, Sanchez O, Diehl JL, COVID-HOP Study Group, Lillo-Le Louet A, Terrier B, Smadja DM.   +28 more
europepmc   +1 more source