Results 1 to 10 of about 10,369 (128)

Preparation of platelet-rich plasma as a tissue adhesive for experimental transplantation in rabbits [PDF]

Thrombosis Journal, 2006
Purpose Platelet-rich plasma (PRP) is an autologous substance with adhesive properties. We aimed at developing and testing the efficacy of a method for PRP preparation in rabbits. Materials and methods An in vitro study was carried out to obtain PRP from
Croxatto Juan, Ferro José, Gatto Silvia, Luengo Gimeno Federico, Gallo Juan   +4 more
doaj   +4 more sources

Reduction of Endothelial Nitric Oxide Increases the Adhesiveness of Constitutive Endothelial Membrane ICAM-1 through Src-Mediated Phosphorylation [PDF]

Frontiers in Physiology, 2018
Nitric oxide (NO) is a known anti-adhesive molecule that prevents platelet aggregation and leukocyte adhesion to endothelial cells (ECs). The mechanism has been attributed to its role in the regulation of adhesion molecules on leukocytes and the adhesive
Feng Gao, Brandon P. Lucke-Wold, Brandon P. Lucke-Wold, Xiang Li, Aric F. Logsdon, Aric F. Logsdon, Li-Chong Xu, Sulei Xu, Kyle B. LaPenna, Huaqi Wang, Huaqi Wang, M. A. Hassan Talukder, Christopher A. Siedlecki, Jason D. Huber, Charles L. Rosen, Pingnian He   +15 more
doaj   +3 more sources

Increased Platelet Adhesiveness in Patients with Venous Thromboembolic Disease [PDF]

TH Open
Julia Martinez-Sanchez, Sergi Torramade-Moix, Ana Belén Moreno-Castaño, Dolors Llobet, Didac Jerez-Dolz, Pablo Sanchez, Marina Carrasco, Sergi Mojal, Carla Moret, Mercedes Camacho, José Manuel Soria, Marta Palomo, Laura Martin-Fernandez, Francisco Vidal, Gines Escolar, Maribel Diaz-Ricart, Juan Carlos Souto   +16 more
doaj   +2 more sources

Method article: an in vitro blood flow model to advance the study of platelet adhesion utilizing a damaged endothelium

Platelets, 2022
In vitro flow assays utilizing microfluidic devices are often used to study human platelets as an alternative to the costly animal models of hemostasis and thrombosis that may not accurately represent human platelet behavior in vivo.
Alison Leigh Banka, Omolola Eniola-Adefeso   +1 more
doaj   +1 more source

CTLs From Patients With Atherosclerosis Show Elevated Adhesiveness and Distinct Integrin Expression Patterns on 2D Substrates

Frontiers in Medicine, 2022
Atherosclerosis is the major cause of cardiovascular disease that is characterized by plaque formation in the blood vessel wall. Atherosclerotic plaques represent sites of chronic inflammation with diverse cell content that is shifted toward the ...
Daria M. Potashnikova, Daria M. Potashnikova, Aleena A. Saidova, Anna V. Tvorogova, Alexandra S. Anisimova, Alexandra S. Anisimova, Alexandra Yu Botsina, Elena Yu Vasilieva, Elena Yu Vasilieva, Leonid B. Margolis   +9 more
doaj   +1 more source

Validated model of platelet slip at stenosis and device surfaces

Platelets, 2020
Platelets are central to thrombosis. However, it is unknown whether platelets slip at vascular or device surfaces. The presence of platelet slip at a surface would interrupt physical contact between the platelet and that surface, and therefore diminish ...
Scott J. Denardo, Bruce C. Denardo, Paul L. Carpinone, William T. Dean, David M. New, Luis E. Estrada, Cynthia L. Green, Paul G. Yock, Gamani Karunasiri   +8 more
doaj   +1 more source

Neutrophil depletion in the pre-implantation phase impairs pregnancy index, placenta and fetus development

Frontiers in Immunology, 2022
Maternal neutrophils cells are players in gestational tolerance and fetus delivery. Nonetheless, their actions in each phase of the pregnancy are unknown.
Cristina Bichels Hebeda, Cristina Bichels Hebeda, Anna Carolina Savioli, Pablo Scharf, Marina de Paula-Silva, Cristiane Damas Gil, Sandra Helena Poliselli Farsky, Silvana Sandri   +7 more
doaj   +1 more source

Effect of dexamethasone therapy on factors of adhesiveness and coagulation in acute lower limb ischemia

Медицинская иммунология, 2023
Leukocyte-platelet adhesion during hypoxia, tissue damage, activation of inflammation and coagulation is associated with the expression of ICAM-1 membrane molecules and integrins by blood and tissue cells.
I. D. Magamedov, L. P. Pivovarova, S. A. Platonov, S. V. Ordynets, S. P. Nokhrin, O. B. Ariskina, I. V. Osipova, K. N. Fomin, A. B. Kurilov, A. I. Tomchenko, V. N. Zhigalo, S. L. Potskhor-ogly, L. V. Kolichenko, O. I. Dyko, T. V. Kopylova, T. A. Isaev   +15 more
doaj   +1 more source

Chemokines, molecular drivers of thromboinflammation and immunothrombosis

Frontiers in Immunology, 2023
Blood clotting is a finely regulated process that is essential for hemostasis. However, when dysregulated or spontaneous, it promotes thrombotic disorders.
Julian Leberzammer, Julian Leberzammer, Julian Leberzammer, Philipp von Hundelshausen, Philipp von Hundelshausen   +4 more
doaj   +1 more source

Platelet signaling--blood's great balancing act [PDF]

, 2015
The antagonistic balance between CalDAG-GEFI and RASA3 signaling is critical for the fine-tuning of platelet adhesiveness, both in the circulation and at sites of vascular ...
Bergmeier, Wolfgang, Stefanini, Lucia
core   +2 more sources