Results 191 to 200 of about 5,594 (244)
Some of the next articles are maybe not open access.
Thrombosis Research, 2011
Platelets play a central role in maintaining hemostasis mainly by binding to subendothelial collagen exposed upon vascular injury, thereby initiating thrombus formation. Platelets can bind directly to the exposed collagen through two major receptors i.e. the integrin a2b1 and glycoprotein (GP) VI.
Benedicte P, Nuyttens +3 more
openaire +2 more sources
Platelets play a central role in maintaining hemostasis mainly by binding to subendothelial collagen exposed upon vascular injury, thereby initiating thrombus formation. Platelets can bind directly to the exposed collagen through two major receptors i.e. the integrin a2b1 and glycoprotein (GP) VI.
Benedicte P, Nuyttens +3 more
openaire +2 more sources
Studies of Platelet Adhesiveness with Reference to Platelet Age
Scandinavian Journal of Haematology, 1969In this study, autologous human platelets labelled with 31Cr were infused in healthy volunteers and their adhesiveness to glass was repeatedly measured during their survival in the circulation using the Salzman's technique. 51Cr‐specific activity was determined seperately for the ‘adhesive’ and ‘non‐adhesive’ platelets and expressed as a ratio of the ...
Z, Rolovic, M G, Baldini
openaire +2 more sources
A Standardized Test of Platelet Adhesiveness
American Journal of Clinical Pathology, 1972An inexpensive and easily constructed glass bead column for determining adhesiveness in vitro is described. The column consists of a flexible paper sipping straw to which a measured quantity of glass beads is added. The column is perfused with heparinized blood at a constant rate of flow.
L R, Zacharski, O R, McIntyre
openaire +2 more sources
The molecular mechanism of platelet adhesion
Australian and New Zealand Journal of Medicine, 1995Abstract:One of the most primitive of host‐defence mechanisms is haemostasis, the ability to control blood loss. In response to vascular trauma, platelets rapidly adhere to the exposed subendothelial matrix, a process that ultimately results in the sealing of the vessel by a plug of platelets stabilised by fibrin.
M C, Berndt +6 more
openaire +2 more sources
Primary Platelet Adhesion Receptors
IUBMB Life, 2005AbstractThrombotic diseases such as heart attack and stroke remain a major health concern in the Western world despite existing anti‐thrombotic drugs. Current studies are revealing structure‐function relationships of primary platelet adhesion receptors mediating adhesion, activation and aggregation, and the molecular mechanisms underlying platelet ...
Jana, Yip +3 more
openaire +2 more sources
Integrin-mediated platelet adhesion
Frontiers in Bioscience, 1998Adhesion of platelets to the damaged subendothelium is a prerequisite reaction for the initiation of hemostasis in vivo. Platelet membranes contain high concentrations of integrins and other glycoproteins (GPs) that are involved in the platelet adhesion to the extracellular matrix.
M, Moroi, S M, Jung
openaire +2 more sources
[Platelet adhesion and adhesive proteins--how to measure the platelet adhesiveness].
Rinsho byori. The Japanese journal of clinical pathology, 1992We examined, platelet adhesive function in vivo by comparing the platelet retention rate (PRR) with other laboratory tests. In 71 patients, PRR did not correlate with bleeding time (BT), ristocetin-induced platelet agglutination (RIPA), vWF:AG, vWF:RCo, FVIII:C, fibrinogen, platelets counts or platelet aggregation tests.
Y, Kawai +3 more
openaire +1 more source
Progress in hemostasis and thrombosis, 1985
Platelets do not adhere to surfaces to which flowing blood is normally exposed in vivo. When the lining of a blood vessel is altered or damaged, however, platelets do adhere to the injured site. Platelet adhesion is one of the first events in the formation of hemostatic plugs and thrombi, and plays a part in the development of atherosclerotic lesions ...
M A, Packham, J F, Mustard
openaire +1 more source
Platelets do not adhere to surfaces to which flowing blood is normally exposed in vivo. When the lining of a blood vessel is altered or damaged, however, platelets do adhere to the injured site. Platelet adhesion is one of the first events in the formation of hemostatic plugs and thrombi, and plays a part in the development of atherosclerotic lesions ...
M A, Packham, J F, Mustard
openaire +1 more source
Studies on Aggregation and Adhesion of Platelets
Thrombosis and Haemostasis, 1967SummaryA modification of the Wright method for the evaluation of the aggregation and adhesive properties of platelets is described; the test is relatively simple and can be performed in a clinical laboratory.Using this procedure, the characteristics of platelets acidified to a pH of 6.5 from their normal pH by addition of small amounts of acid citrate ...
J A, Shively, C L, Gott
openaire +2 more sources
Aggregation and Adhesion of Rat Platelets
Nature, 1967Aggregation of rat platelets caused by ADP is inhibited by adenosine in citrated but not in heparinized plasma. Rat platelets are less sensitive to aggregation by collagen than are human and rabbit platelets, which may be related to the in vivo formation and inhibition of platelet thrombi in rat vessels.
openaire +2 more sources