Results 121 to 130 of about 235,538 (306)

Hepatic thrombopoietin gene silencing reduces platelet count and breast cancer progression in transgenic MMTV-PyMT mice

Blood Advances, 2019
: In humans, platelet count within the normal range is required for physiological hemostasis, but, adversely, platelets also support pathological thrombosis. Moreover, by releasing growth factors, they may enhance neoplastic proliferation. We hypothesize
Toshiaki Shirai, Alexey S. Revenko, Justin Tibbitts, Anh T.P. Ngo, Annachiara Mitrugno, Laura D. Healy, Jennifer Johnson, Erik I. Tucker, Monica T. Hinds, Lisa M. Coussens, Owen J.T. McCarty, Brett P. Monia, András Gruber   +12 more
doaj  

Elevated platelet count as a cause of abnormal von Willebrand factor multimer distribution in plasma [PDF]

, 1993
Ulrich Budde, Scharf Re, P. Franke, K Hartmann-Budde, J Dent, ZM Ruggeri   +5 more
openalex   +1 more source

Toward Enhancing Chiro‐Optical and Magneto‐Optical Properties of Magnetic Nanocrystals by Surface Plasmons

Advanced Optical Materials, EarlyView.
Here, recent progress is highlighted in colloidal magnetoplasmonic hybrid nanomaterials, with a focus on chiral plasmonics. Metal nanocrystals with intrinsic chiroptical features can lead to a combination of chiral plasmonics and magneto‐optics effects when interacting with the magnetic counterpart, offering a foundation for systematically designing ...
Miguel Comesaña‐Hermo, Eloi Haltz, Alessio Gabbani, Francesco Pineider, Verónica Salgueiriño   +4 more
wiley   +1 more source

Haematocrit, leukocyte and platelet counts and the severity of the ovarian hyperstimulation syndrome [PDF]

, 1998
F. Fàbregues, Juan Balasch, Dolors Manau, Wladimiro Jiménez, Vicente Arroyo, Montse Tuset Creus, Francisca Rivera, Juan A. Vanrell   +7 more
openalex   +1 more source

AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells

Advanced Science, EarlyView.
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu, Guisheng Chen, Rui Hu, Peiwen Liu, Jintao Lou, Wenji Zhao, Zuhong He, Suhua Sha, Yiqing Zheng   +8 more
wiley   +1 more source

Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion

Advanced Science, EarlyView.
sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin, Lianhua Yin, Weilin Liu, Rui Li, Tao Jiang, Minguang Yang, Yajun Cao, Sinuo Wang, Yan Yu, Cong Chen, Xiaoqin Guo, Wenju Wang, Huanhuan Liu, Yaling Dai, Jiamin Yan, Yanting Lin, Yanyi Ding, Chendong Ruan, Lei Yang, Tiecheng Wu, Jing Tao, Lidian Chen   +21 more
wiley   +1 more source

Alteration in platelet count and aggregation after splenectomy

, 1977
Isao Kamisasa, S Ichihara, Ko HIDAI, Kagemitsu Ninomiya, Mitsuo Sugiura, Manabu YAMANAKA   +5 more
openalex   +2 more sources

Tailoring a Functional Synthetic Microbial Community Alleviates Fusobacterium nucleatum‐infected Colorectal Cancer via Ecological Control

Advanced Science, EarlyView.
The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou, Mengyue Yang, Hong Fang, Baizhuo Zhang, Yunhao Ma, Yongyuan Li, Yingjie Liu, Zeying Cheng, Yuanchun Zhao, Zhenzhen Si, Hongmei Zhu, Peng Chen   +11 more
wiley   +1 more source

RIG‐I‐Inducing Small Molecules Potently Inhibit HMA‐Resistant AML Through Igniting the Overloaded dsRNA Arsenal

Advanced Science, EarlyView.
This study reveals a novel mechanism of resistance to DNA hypomethylating agents (HMAs) in acute myeloid leukemia (AML), and identifies all‐trans retinoic acid (ATRA) and tamibarotene (TAM) as potent agents that overcome HMA resistance by reactivating the interferon anticancer immune response. The findings offer promising therapeutic strategies for HMA‐
Xueqin Chen, Jiaqi Wu, Yuntong Li, Jiayu Huang, Xiangqin Weng, Jiale Wu, Shujun Xiao, Huaxin Song, Zhengyuan Wang, Ni Yan, Fangfang Shi, Derun Zheng, Kai Tan, Hesong Zhang, Jingyi Cui, Wen Wu, Wei Wu, Sujiang Zhang, Min Lu   +18 more
wiley   +1 more source

Prognostic study of continuous variables (white blood cell count, peripheral blast cell count, haemoglobin level, platelet count and age) in childhood acute lymphoblastic leukaemia. Analysis of a population of 1545 children treated by the French Acute Lymphoblastic Leukaemia Group (FRALLE) [PDF]

, 2000
Jean Donadieu, M-F Auclerc, André Baruchel, Yves Pérel, Pierre Bordigoni, Judith Landman‐Parker, Thierry Leblanc, G. Cornu, D. Sommelet, Guy Leverger, G Schaison, Catherine Hill   +11 more
openalex   +1 more source