Results 161 to 170 of about 378,593 (354)

Mucous Permeable Nanoparticle for Inducing Cuproptosis‐Like Death In Broad‐Spectrum Bacteria for Nebulized Treatment of Acute Pneumonia

open access: yesAdvanced Science, EarlyView.
Copper‐based nanoparticles doped with BSO, and modified with PEG, not only can it increase the retention ability and mucosal penetration ability in the lungs, but also induce cuproptosis‐like death in bacteria and inhibit bacterial TCA cycle. It can also inhibit bacterial quorum sensing, clear biofilms, reduce bacterial virulence, and thus exert ...
Huiqun Hu   +9 more
wiley   +1 more source

Use of hematological parameters in evaluation of treatment efficacy in cutaneous leishmaniasis

open access: yes, 2015
Objective: In the present study we investigated the role of hematological parameters, including neutrophil/lymphocyte ratio and platelet/lymphocyte ratio, mean platelet volume and platelet distribution width in the evaluation of treatment efficacy in ...
Bilal Sula, Recep Tekin
core   +2 more sources

AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells

open access: yesAdvanced Science, EarlyView.
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu   +8 more
wiley   +1 more source

Changes in Serial Platelet Counts Following Massive Blood Transfusion in Pediatric Patients [PDF]

open access: bronze, 1985
Charles J. Coté   +4 more
openalex   +1 more source

Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao   +15 more
wiley   +1 more source

Cooperative SIR dynamics as a model for spontaneous blood clot initiation [PDF]

open access: yesarXiv
Blood clotting is an important physiological process to suppress bleeding upon injury, but when it occurs inadvertently, it can cause thrombosis, which can lead to life threatening conditions. Hence, understanding the microscopic mechanistic factors for inadvertent, spontaneous blood clotting, in absence of a vessel breach, can help in predicting and ...
arxiv  

Pathophysiological aspects of Platelet-Mediated Thrombosis and Bleeding in Essential Thrombocythemia: [PDF]

open access: yes, 1998
Thrombocytosis, i.e. an elevation of the platelet count, is a common finding in clinical practice. In general, patients with thrombocytosis are distinguished into two main categories, primarily based on the cause underlying the increased platelet count ...
Genderen, P.J.J. (Perry) van
core   +1 more source

Assessment Prevalence of Thrombocytopenia in Chronic Hepatitis B and C [PDF]

open access: yes
Thrombocytopenia is a common complication in chronic liver disease characterized by a low platelet count, which is lower than the normal platelet count < 150 X10 9.
Durib, Ali Kareem   +2 more
core   +2 more sources

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