Results 11 to 20 of about 112,923 (261)
Inherited platelet disorders [PDF]
AbstractObjectiveTo present the latest information on inherited platelet disorders in domestic animals.Data SourcesResearch articles and reviews spanning 40 years available on PubMed.Human Data SynthesisInformation regarding inherited platelet disorders in people is plentiful and often descriptions of human conditions have led to the identification of ...
A T, Nurden, K, Freson, U, Seligsohn
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Thrombotic thrombocytopenic purpura (TTP) is a rare, serious, life-threatening disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, and hypercoagulability.
Bahjat Azrieh +9 more
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Management of siblings with Glanzmann's thrombasthenia: A case report
Glanzmann's thrombasthenia is a rare, genetically inherited platelet disorder characterized by a lack of platelet aggregation. Until date, only close to 500 cases have been reported.
Mebin George Mathew
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Do platelet indices play a role in assessing severity of pre-eclampsia and eclampsia?
Background: Pre-eclampsia and eclampsia is a multisystem disorder affecting approximately 2-7% of all pregnancies and is a significant cause of maternal and fetal morbidity and mortality.
Priyamvada Singhal +3 more
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Genomics of platelet disorders [PDF]
Genetic diagnosis in families with inherited platelet disorders (IPD) is not performed widely because of the genetic heterogeneity of this group of disorders and because in most cases, it is not possible to select single candidate genes for analysis using clinical and laboratory phenotypes. Next‐generation sequencing (NGS) technology has revolutionized
S. K. Westbury, A. D. Mumford
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Platelets in psychiatric disorders
Several parallels exist between platelets and the brain, which make them interesting for studying the neurobiology of psychiatric disorders, such as Alzheimer's disease, depression, schizophrenia and anxiety disorders. Platelets store, secrete and process the amyloid precursor protein which is cleaved into the β-amyloid (Aβ) peptides.
Daniela, Ehrlich, Christian, Humpel
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Platelet glycoprotein VI genetic quantitative and qualitative defects
Platelet membrane glycoprotein VI (GPVI) is increasingly recognized as an important receptor for thrombus formation and growth. Numerous arguments have been published indicating that GPVI plays a major role in thrombosis without being essential for ...
Martine Jandrot-Perrus +2 more
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Hematological and surgical management in Glanzmann′s thrombasthenia: A case report
Glanzmann′s thrombasthenia (GT) is a rare, congenital, and moderate to severe platelet disorder. The bleeding time is increased, due to lack of platelet aggregation, since the patients with GT have deficient or dysfunctional integrin membrane ...
Anjana Gopalakrishnan +2 more
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Hermansky Pudlak Syndrome Type 2:A Rare Case Report [PDF]
Hermansky-Pudlak Syndrome (HPS) is a rare autosomal recessive disorder characterized by Oculocutaneous Albinism (OCA), platelet disorder, and ceroid accumulation. It is common in North West Puerto Rico region, and the incidence reported is 1/500000.
Yogesh Chhaparwal +2 more
doaj
Objective Platelets are increasingly considered to play an important role in inflammation and are being regarded as a putative bridge linking mental diseases and inflammatory response. Platelet-associated haematological parameters including mean platelet
Yanyan Wei +6 more
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