Results 211 to 220 of about 112,923 (261)
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Platelets and platelet disorders in Africa
Baillière's Clinical Haematology, 1992Blood platelets, which are known to play important roles in normal vertebrate biology, are influenced by a variety of factors, the majority of which are acquired. In this chapter, attention is drawn to the need to re-examine one of the old accepted values in haematology, the normal platelet count.
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Disorders of Platelets in Pregnancy
Obstetrical & Gynecological Survey, 1994No significant change in platelet number, function or life-span occurs during pregnancy. However, pregnancy may be complicated by various platelet abnormalities or platelets may be involved in pregnancy pathologies. Thrombocytopenia is the most common platelet disorder to affect pregnancy. It may occur in a number of clinical conditions and both immune
A, Biswas, S, Arulkumaran, S S, Ratnam
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Platelet disorders in pregnancy
Current Opinion in Obstetrics and Gynecology, 2001Before the advent of automated cell counters, thrombocytopenia was looked for and identified after a clinical question. With automation, thrombocytopenia in pregnancy was commonly found, and with its commonality its clinical meaning went out of focus. For the majority of women, thrombocytopenia is benign and, as a marker of fetal thrombocytopenia, the ...
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The Lancet, 1981
The hypothesis that migraine is caused by a primary abnormality of platelet behaviour was investigated in a total of 77 migraine patients and control subjects. Platelets taken from patients with classical migraine during a headache-free period demonstrated significantly higher spontaneous platelet aggregation and platelet adhesion than platelets from ...
E, Hanington +3 more
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The hypothesis that migraine is caused by a primary abnormality of platelet behaviour was investigated in a total of 77 migraine patients and control subjects. Platelets taken from patients with classical migraine during a headache-free period demonstrated significantly higher spontaneous platelet aggregation and platelet adhesion than platelets from ...
E, Hanington +3 more
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Thrombosis Research, 2016
In contrast to congenital platelet disorders, which are rare, acquired platelet dysfunctions are more common in clinical practice. Their main causes are medications and systemic/hematologic diseases. Typical clinical manifestations are mucosal bleeding, epistaxis, or superficial epidermal bleeding normally of modest entity. In most cases, the molecular
Caterina, Casari, Wolfgang, Bergmeier
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In contrast to congenital platelet disorders, which are rare, acquired platelet dysfunctions are more common in clinical practice. Their main causes are medications and systemic/hematologic diseases. Typical clinical manifestations are mucosal bleeding, epistaxis, or superficial epidermal bleeding normally of modest entity. In most cases, the molecular
Caterina, Casari, Wolfgang, Bergmeier
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Haemophilia, 2000
Platelet function defects comprise a large and heterogeneous group of bleeding disorders that range in severity from mild to severe. Patients may be asymptomatic; however, the majority who are diagnosed present with easy bruising and mucocutaneous bleeding, or with excessive haemorrhage following injury or surgery.
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Platelet function defects comprise a large and heterogeneous group of bleeding disorders that range in severity from mild to severe. Patients may be asymptomatic; however, the majority who are diagnosed present with easy bruising and mucocutaneous bleeding, or with excessive haemorrhage following injury or surgery.
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Critical Reviews in Oncology/Hematology, 1986
The present review has cataloged the inherited and acquired disorders of platelet granules. Unfortunately, a mere listing of different conditions in which dense bodies, alpha granules, or both are decreased, absent, or fused does little to define their importance in human platelet physiology or as a causative factor in hemorrhagic disease.
James G. White, Harvey J. Weiss
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The present review has cataloged the inherited and acquired disorders of platelet granules. Unfortunately, a mere listing of different conditions in which dense bodies, alpha granules, or both are decreased, absent, or fused does little to define their importance in human platelet physiology or as a causative factor in hemorrhagic disease.
James G. White, Harvey J. Weiss
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Hematology, 2005
Abstract The inherited platelet disorders are a heterogeneous collection of rare diseases that are infrequently encountered in clinical practice. They are, however, fascinating abnormalities, which have taught us a great deal about normal platelet biochemistry and physiology.
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Abstract The inherited platelet disorders are a heterogeneous collection of rare diseases that are infrequently encountered in clinical practice. They are, however, fascinating abnormalities, which have taught us a great deal about normal platelet biochemistry and physiology.
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Disorders of platelet function
Disease-a-Month, 1992Platelets provide for primary hemostasis by forming a hemostatic plug at sites of vascular damage. They also provide a surface for the assembly of the coagulation protein complexes that generate thrombin, serve as a nidus for fibrin clots, and secrete factors involved in wound repair.
J S, Bennett, M A, Kolodziej
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Platelet Disorders in Pregnancy
Clinics in Perinatology, 1980This article focuses on the platelet component of hemostasis during pregnancy, and on abnormalities in coagulation attributable to a decrease in platelet number, qualitative platelet function, or both. The restrictions that pregnancy imposes on the evaluation and treatment of these hemostatic abnormalities are emphasized.
R, Romero, T P, Duffy
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