Results 91 to 100 of about 6,659 (141)

Histological differences among thrombi in thrombotic diseases. [PDF]

Curr Opin Hematol
Yamashita A, Gi T, Sato Y.
europepmc   +1 more source

The role of platelet desialylation as a biomarker in primary immune thrombocytopenia: mechanisms and therapeutic perspectives. [PDF]

Front Immunol
Zhang Q, Huang M, Thomas ER, Wang L, Liu J, Li X, Luo J, Zou W, Wu J.   +8 more
europepmc   +1 more source

Clinical Management of a Rare Hereditary Bleeding Disorder in an Adult: Glanzmann Thrombasthenia. [PDF]

Cureus
Mecca R, Senthil N, Lakshmanan S, Anna Anil A.   +3 more
europepmc   +1 more source

Effects of fibrinogen receptor antagonist GR144053F and aurintricarboxylic acid on platelet activation and degranulation11Abbreviations: ACD, citric acid/trisodium citrate/glucose (recipe A), blood anticoagulant; ATA, aurintricarboxylic acid; CTCADP, closure (occlusion) time determined with the use of collagen/ADP cassettes in PFA-100; GPIb-IX-V, a complex of glycoproteins Ib, IX, and V, a vWF receptor; GPIIb-IIIa, a complex of glycoproteins IIb and IIIa, a fibrinogen receptor; ic50, the …

Biochemical Pharmacology, 2001
Activated blood platelets play crucial role in restenosis due to their fundamental significance in thrombus formation. Therefore, platelets are attractive targets for the inhibition with a variety of antagonists. In this study, we present direct evidence that GR144053F [non-peptide antagonist of glycoprotein IIb-IIIa complex (GPIIb-IIIa)] inhibits ...
M. Różalski, Magdalena Boncler, Jacek Golański, Cezary Watała   +3 more
openalex   +4 more sources

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Alteration in GPIIb/IIIa Binding of VWD-Associated von Willebrand Factor Variants with C-Terminal Missense Mutations

Thrombosis and Haemostasis, 2019
The platelet receptor glycoprotein (GP) IIb/IIIa, formed by integrins αIIb and β3, plays an important role in platelet adhesion and aggregation. Its major binding site is the arginine-glycine-aspartic acid (RGD) sequence present in several adhesive ...
G. König, T. Obser, O. Marggraf, S. Schneppenheim, U. Budde, R. Schneppenheim, M. Brehm   +6 more
semanticscholar   +1 more source

The Fluid-phase SC5b-9 Terminal Complement Complex Binds to the GPIIb/IIIa Complex of Thrombin-stimulated Human Blood Platelets Inhibiting Platelet Aggregation.

Platelets, 1995
M. Røger, K. Høgåsen, P. Holme, T. Halstensen, T. Mollnes, T. Hovig   +5 more
semanticscholar   +1 more source

Combined defect in membrane expression and activation of platelet GPIIb–IIIa complex without primary sequence abnormalities in myeloproliferative disease

British Journal of Haematology, 2000
R. Kaplan, J. Gabbeta, Ling Sun, G. Mao, A. Rao   +4 more
semanticscholar   +1 more source

Identification of Clinicopathological Spectrum, Platelet Glycoprotein IIb/IIIa complex and Platelet Antibodies in Egyptian Children with Glanzmann’s Thrombasthenia

Archivum Immunologiae et Therapiae Experimentalis, 2017
Asmaa M. Zahran, K. Saad, Khalid I. Elsayh, M. Alblihed, Mostafa M. Embaby   +4 more
semanticscholar   +1 more source