Results 11 to 20 of about 6,842 (128)

Simultaneous release of a hydroxy-methylglutaryl coenzyme A reductase inhibitor and a glycoprotein IIb/IIIa antagonist from a thermoresponsive NiPAAm/NtBAAm copolymer system. [PDF]

open access: yes, 2011
While deployment of intracoronary stents has been shown to reduce restenosis, stenting can also damage the endothelial was eluted during this period.
Cox, Dermot   +4 more
core   +1 more source

Acute cardiac inflammatory responses to postischemic reperfusion during cardiopulmonary bypass [PDF]

open access: yes, 1999
Objectives: The investigation centers on whether there is a reperfusion-induced specific cardiac inflammatory reaction after bypass surgery. Background: Cardiopulmonary bypass (CPB) leads to systemic inflammation.
Becker, Bernhard F.   +5 more
core   +1 more source

Abciximab‐Associated Thrombocytopenia After Previous Tirofiban‐Related Thrombocytopenia [PDF]

open access: yes, 2006
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90080/1/phco.26.3.423 ...
Dorsch, Michael P.   +3 more
core   +1 more source

A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary thrombosis. [PDF]

open access: yes, 1996
BACKGROUND: Platelet glycoprotein IIb/IIIa is a membrane receptor for fibrinogen and von Willebrand factor, and it has an important role in platelet aggregation. It is known to be involved in the pathogenesis of acute coronary syndromes.
Becker, Lewis C   +8 more
core   +2 more sources

Integrins as therapeutic targets: lessons and opportunities. [PDF]

open access: yes, 2010
The integrins are a large family of cell adhesion molecules that are essential for the regulation of cell growth and function. The identification of key roles for integrins in a diverse range of diseases, including cancer, infection, thrombosis and ...
A Artoni   +199 more
core   +1 more source

New in vitro effects of clopidogrel on platelets in hyperlipidemic and healthy subjects [PDF]

open access: yes, 2010
Objective: We aimed to detect novel in vitro effects of clopidogrel on platelets by assessment of the following parameters: malondialdehyde, glutathione, nitrite, aggregation response, and expressions of P-selectin, fibrinogen, apolipoprotein A1 ...
Azize Şener   +5 more
core   +2 more sources

Identification of 22 novel mutations in patients with Glanzmann's thrombasthenia [PDF]

open access: yes, 2008
Glanzmann's thrombasthenia (GT) is an autosomal recessive inherited platelet function defect that characterized by reduction in, or absence of, platelet aggregation in response to multiple physiologic agonists. GT is characterized by normal platelet
Abdul Ethayathulla   +6 more
core   +1 more source

The interaction of bacterial pathogens with platelets. [PDF]

open access: yes, 2006
In recent years, the frequency of serious cardiovascular infections such as endocarditis has increased, particularly in association with nosocomially acquired antibiotic-resistant pathogens. Growing evidence suggests a crucial role for the interaction of
A Copley   +177 more
core   +1 more source

Gene mutations of platelet glycoproteins and response to tirofiban in acute coronary syndrome

open access: yesSão Paulo Medical Journal
CONTEXT AND OBJECTIVES: Glycoprotein inhibitors (abciximab, eptifibatide and tirofiban) are used in patients with unstable angina and non-ST-segment elevation myocardial infarction before percutaneous coronary intervention.
Antonio de Padua Mansur   +5 more
doaj   +1 more source

Distinct functions of integrin alpha and beta subunit cytoplasmic domains in cell spreading and formation of focal adhesions. [PDF]

open access: yes, 1993
Integrin-mediated cell adhesion often results in cell spreading and the formation of focal adhesions. We exploited the capacity of recombinant human alpha IIb beta 3 integrin to endow heterologous cells with the ability to adhere and spread on fibrinogen
Chen, Y   +5 more
core  

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